Varaico: Literature-Extracted Genetic Variants

Gene:IDH1
Variant:p.G70D
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IDH1

NM_005896.4:p.G70D

Associated Papers

Protein Tyrosine Phosphatase Non-Receptor 11 (PTPN11/Shp2) as a Driver Oncogene and a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC).

Richards CE et al.

International Journal of Molecular Sciences, 2023

37445722 (PubMed )
Supplement: ijms-24-10545-s001.zip › PTPN11_paper_supplementary_tables_25042023.pdf

Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Sobahy TM et al.

Bmc Medical Genomics, 2022

35468810 (PubMed )
Supplement: 12920_2022_1235_MOESM2_ESM.xlsx › Sheet1

Molecular Alterations in Thyroid Cancer: From Bench to Clinical Practice.

Tirrò E et al.

Genes, 2019

IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis.

Gao Y et al.

Plos One, 2018

Role of isocitrate dehydrogenase 1/2 (IDH 1/2) gene mutations in human tumors.

Liu X et al.

Histology and Histopathology, 2015

IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in glioma.

Zhang C et al.

Neuro-oncology, 2013

IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives.

Yang H et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2012

Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production.

Ward PS et al.

Oncogene, 2012

Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas.

Hemerly JP et al.

European Journal of Endocrinology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."