Varaico: Literature-Extracted Genetic Variants

Gene:IDH2
Variant:p.W132L
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IDH2

NM_002168.4:p.W132L

Associated Papers

Evaluation of the rapid Idylla IDH1-2 mutation assay in FFPE glioma samples.

Solomon JP et al.

Diagnostic Pathology, 2024

38796421 (PubMed )
Supplement: 13000_2024_1492_MOESM1_ESM.docx

Impact of IDH1 and IDH2 mutation detection at diagnosis and in remission in patients with AML receiving allogeneic transplantation.

Bill M et al.

Blood Advances, 2023

35381077 (PubMed )
Supplement: BLOODA_ADV-2021-005789-mmc1.pdf

Mutational landscape and genetic signatures of cell-free DNA in tumour-induced osteomalacia.

Wu N et al.

Journal of Cellular and Molecular Medicine, 2020

32277576 (PubMed )
Supplement: JCMM-24-4931-s008.xlsx › Sheet1

Advances in sarcoma gene mutations and therapeutic targets.

Gao P et al.

Cancer Treatment Reviews, 2018

Isocitrate dehydrogenase mutations in gliomas.

Waitkus MS et al.

Neuro-oncology, 2016

Molecular profiling of intrahepatic and extrahepatic cholangiocarcinoma using next generation sequencing.

Putra J et al.

Experimental and Molecular Pathology, 2015

Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma.

Borger DR et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2014

IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders.

Zou Y et al.

Biochemical and Biophysical Research Communications, 2010

IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors.

Bleeker FE et al.

Human Mutation, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."