Varaico: Literature-Extracted Genetic Variants

Gene:IFNAR2
Variant:p.E77A
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IFNAR2

NM_001289125.3:p.E77A

Associated Papers

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling.

de Weerd NA et al.

The Journal of Biological Chemistry, 2017

Structural linkage between ligand discrimination and receptor activation by type I interferons.

Thomas C et al.

Cell, 2011

The human type I interferon receptor: NMR structure reveals the molecular basis of ligand binding.

Chill JH et al.

Structure (london, England : 1993), 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."