Associated Papers
Functional characterization of a clinically significant variant of IGF1R (M1054I) - a critical residue involved in defining the binding of small molecules in the allosteric pocket of IGF1R.
Showket F et al.
Growth Factors (chur, Switzerland), 2025
Identification of a stretch of four discontinuous amino acids involved in regulating kinase activity of IGF1R.
Qadir Bhat A et al.
Journal of Cell Science, 2022
Analyzing structural differences between insulin receptor (IR) and IGF1R for designing small molecule allosteric inhibitors of IGF1R as novel anti-cancer agents.
Bano N et al.
Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society, 2020
Identification of a unique loss-of-function mutation in IGF1R and a crosstalk between IGF1R and Wnt/β-catenin signaling pathways.
Jamwal G et al.
Biochimica Et Biophysica Acta. Molecular Cell Research, 2018
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