Associated Papers
Alpha-Synuclein Neurobiology in Parkinson's Disease: A Comprehensive Review of Its Role, Mechanisms, and Therapeutic Perspectives.
Pitton Rissardo J et al.
Brain Sciences, 2025
Insights Into Retinal Pathologies in Neurological Disorders: A Focus on Parkinson's Disease, Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Alzheimer's Disease.
Akyuz E et al.
Journal of Neuroscience Research, 2025
TOLLIP acts as a cargo adaptor to promote lysosomal degradation of aberrant ER membrane proteins.
Hayashi Y et al.
The Embo Journal, 2023
37929762 (PubMed )
Supplement: EMBJ-42-e114272-s006.pdf
Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice.
Lloyd GM et al.
Acta Neuropathologica, 2022
Role of lysosomes in physiological activities, diseases, and therapy.
Zhang Z et al.
Journal of Hematology & Oncology, 2021
Targeting of Lysosomal Pathway Genes for Parkinson's Disease Modification: Insights From Cellular and Animal Models.
Abe T et al.
Frontiers in Neurology, 2021
Dynamin-related protein 1: A protein critical for mitochondrial fission, mitophagy, and neuronal death in Parkinson's disease.
Feng ST et al.
Pharmacological Research, 2020
Current Evidence for a Bidirectional Loop Between the Lysosome and Alpha-Synuclein Proteoforms.
Wildburger NC et al.
Frontiers in Cell and Developmental Biology, 2020
Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein.
Krejciova Z et al.
Acta Neuropathologica Communications, 2019
Familial Parkinson's point mutation abolishes multiple system atrophy prion replication.
Woerman AL et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018
Autophagy and Alpha-Synuclein: Relevance to Parkinson's Disease and Related Synucleopathies.
Xilouri M et al.
Movement Disorders : Official Journal of the Movement Disorder Society, 2016
Part II: alpha-synuclein and its molecular pathophysiological role in neurodegenerative disease.
Dev KK et al.
Neuropharmacology, 2003
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