Varaico: Literature-Extracted Genetic Variants

Gene:IGF2R
Variant:p.G1449V
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IGF2R

NM_000876.4:p.G1449V

Associated Papers

Large-scale analysis of variation in the insulin-like growth factor family in humans reveals rare disease links and common polymorphisms.

Rotwein P

The Journal of Biological Chemistry, 2017

M6P/IGF2R tumor suppressor gene mutated in hepatocellular carcinomas in Japan.

Oka Y et al.

Hepatology (baltimore, Md.), 2002

Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur.

Brown J et al.

The Embo Journal, 2002

Mannose 6-phosphate/insulin-like growth factor 2 receptor, a bona fide tumor suppressor gene or just a promising candidate?

DaCosta SA et al.

Journal of Mammary Gland Biology and Neoplasia, 2000

Altered ligand binding by insulin-like growth factor II/mannose 6-phosphate receptors bearing missense mutations in human cancers.

Devi GR et al.

Cancer Research, 1999

Disruption of ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor by cancer-associated missense mutations.

Byrd JC et al.

The Journal of Biological Chemistry, 1999

M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity.

De Souza AT et al.

Nature Genetics, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."