Varaico: Literature-Extracted Genetic Variants

Gene:IGF2R
Variant:p.N2020S
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IGF2R

NM_000876.4:p.N2020S

Associated Papers

Accurate affinity models for SH2 domains from peptide binding assays and free-energy regression.

Gagoski D et al.

Protein Science : a Publication of the Protein Society, 2025

41088778 (PubMed )
Supplement: PRO-34-e70317-s008.xlsx › _S6_-_PTMVar_-_Lyn

Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression.

Gagoski D et al.

Biorxiv : the Preprint Server for Biology, 2025

39764007 (PubMed )
Supplement: media-1.xlsx › _S6_-_PTMVar_-_Lyn

A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC).

Low JL et al.

Ebiomedicine, 2021

33529999 (PubMed )
Supplement: mmc2.xlsx › Table_S2

Large-scale analysis of variation in the insulin-like growth factor family in humans reveals rare disease links and common polymorphisms.

Rotwein P

The Journal of Biological Chemistry, 2017

The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.

Tang X et al.

Nucleic Acids Research, 2014

25352556 (PubMed )
Supplement: supp_gku1005_nar-01266-met-n-2014-File012.xlsx › TCGA-A2-A04Y-01A.domain

IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites.

Hoyo C et al.

Disease Markers, 2012

IGF2R polymorphisms and risk of esophageal and gastric adenocarcinomas.

Hoyo C et al.

International Journal of Cancer, 2009

Insulin-like growth factor 2 (IGF2) and IGF2 receptor gene variants are associated with fetal growth.

Kaku K et al.

Acta Paediatrica (oslo, Norway : 1992), 2007

Genetic variation in the type 2 insulin-like growth factor receptor gene and disparity in childhood height.

Petry CJ et al.

Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society, 2005

Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur.

Brown J et al.

The Embo Journal, 2002

Mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) variants in American and Japanese populations.

Killian JK et al.

Human Mutation, 2001

A common polymorphism in exon 40 of the human mannose 6-phosphate/insulin-like growth factor II receptor gene.

Zhong X et al.

Molecular and Cellular Probes, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."