Associated Papers
TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO.
Yu Z et al.
Signal Transduction and Targeted Therapy, 2021
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz M et al.
Molecular Cell, 2010
ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress.
Wu ZH et al.
Molecular Cell, 2010
DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding.
Grubisha O et al.
Journal of Molecular Biology, 2010
The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL.
Lamothe B et al.
The Journal of Biological Chemistry, 2008
Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation.
Conze DB et al.
Molecular and Cellular Biology, 2008
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation.
Oeckinghaus A et al.
The Embo Journal, 2007
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].
Wu CJ et al.
Nature Cell Biology, 2006
The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation.
Makris C et al.
Molecular and Cellular Biology, 2002
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