Associated Papers
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia.
Aubrey BJ et al.
Nature Cancer, 2022
Novel Molecular Mechanism of Lenalidomide in Myeloid Malignancies Independent of Deletion of Chromosome 5q.
Park I et al.
Cancers, 2021
Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.
Sievers QL et al.
Science (new York, N.y.), 2018
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Matyskiela ME et al.
Nature, 2016
A calcium- and calpain-dependent pathway determines the response to lenalidomide in myelodysplastic syndromes.
Fang J et al.
Nature Medicine, 2016
Structural basis of lenalidomide-induced CK1α degradation by the CRL4(CRBN) ubiquitin ligase.
Petzold G et al.
Nature, 2016
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