Associated Papers
Genomic Subclassification and Risk Stratification of ALL.
Østergaard A et al.
Acta Haematologica, 2026
B-cell lymphoblastic leukemia/lymphoma with mutated IKZF1 N159Y: clinical and genetic features of an emerging entity.
Alvey EN et al.
Haematologica, 2025
Leveraging genomic diagnostics for prognostics and therapeutics in pediatric acute leukemia.
Newman H et al.
Hemasphere, 2025
Novel molecular mechanisms of FLT3 deregulation: from the acute myeloid leukemia experience to therapeutic insights in acute lymphoblastic leukemia.
Lo Schiavo F et al.
Molecular Cancer, 2025
Age-Driven Genetic and Epigenetic Heterogeneity in B-ALL.
Veselinova Y et al.
International Journal of Molecular Sciences, 2025
A Comprehensive Review of Somatic and Germline Biomarkers Associated with Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: From Biological Significance to Precision Medicine Opportunities.
Martínez Anaya D et al.
Biomedicines, 2025
Heterogeneity of IKZF1 genomic alterations and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia.
Wang'ondu RW et al.
Leukemia, 2025
Molecular Profiling Reveals Novel Gene Fusions and Genetic Markers for Refined Patient Stratification in Pediatric Acute Lymphoblastic Leukemia.
Péterffy B et al.
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2025
How to combine multiple tools for the genetic diagnosis work-up of pediatric B-cell acute lymphoblastic leukemia.
Hidalgo-Gómez G et al.
Annals of Hematology, 2025
Diagnostic genomic analysis is prognostic in AYA patients with ALL treated on an MRD-stratified pediatric protocol.
Yeung DT et al.
Blood Neoplasia, 2025
Identification of a novel TOP2B::AFF2 fusion gene in B-cell acute lymphoblastic leukemia.
Liu T et al.
Scientific Reports, 2025
Genetic characterization of pediatric B-cell acute lymphoblastic leukemia in Argentina uncovers molecular heterogeneity and novel variants.
Sol Ruiz M et al.
Frontiers in Pharmacology, 2025
Unraveling the Genetic Heterogeneity of Acute Lymphoblastic Leukemia Based on NGS Applications.
Ramírez Maldonado V et al.
Cancers, 2024
Heterogeneity of IKZF1 genomic alterations and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia.
Mullighan C et al.
Research Square, 2024
Genomic profiling of pediatric hematologic malignancies and diagnosis of cancer predisposition syndromes: tumoronly versus paired tumor-normal sequencing.
Newman H et al.
Haematologica, 2024
A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children.
de Smith AJ et al.
Cell Genomics, 2024
Predictive and prognostic molecular biomarkers in lymphomas.
Iorgulescu JB et al.
Pathology, 2024
Transcriptome Sequencing Allows Comprehensive Genomic Characterization of Pediatric B-Acute Lymphoblastic Leukemia in an Academic Clinical Laboratory.
Hu Z et al.
The Journal of Molecular Diagnostics : Jmd, 2024
Pediatric Hematopathology in the Era of Advanced Molecular Diagnostics: What We Know and How We Can Apply the Updated Classifications.
Liu YC et al.
Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology, 2024
IKZF1plus is a frequent biomarker of adverse prognosis in Mexican pediatric patients with B-acute lymphoblastic leukemia.
Garcia-Solorio J et al.
Frontiers in Oncology, 2024
Multifaceted roles of IKZF1 gene, perspectives from bench to bedside.
Feng L et al.
Frontiers in Oncology, 2024
Clinically relevant core genes for hematologic malignancies in clinical NGS panel testing.
Song JS
Blood Research, 2023
Epigenomic mapping reveals distinct B cell acute lymphoblastic leukemia chromatin architectures and regulators.
Barnett KR et al.
Cell Genomics, 2023
Outlier Expression of Isoforms by Targeted or Total RNA Sequencing Identifies Clinically Significant Genomic Variants in Hematolymphoid Tumors.
Tsai HK et al.
The Journal of Molecular Diagnostics : Jmd, 2023
Epigenomic mapping in B-cell acute lymphoblastic leukemia identifies transcriptional regulators and noncoding variants promoting distinct chromatin architectures.
Barnett KR et al.
Biorxiv : the Preprint Server for Biology, 2023
Classification and genetics of pediatric B-other acute lymphoblastic leukemia by targeted RNA sequencing.
Migita NA et al.
Blood Advances, 2023
Identification of IKZF1 genetic mutations as new molecular subtypes in acute myeloid leukaemia.
Wang Y et al.
Clinical and Translational Medicine, 2023
Emerging molecular subtypes and therapies in acute lymphoblastic leukemia.
Davis K et al.
Seminars in Diagnostic Pathology, 2023
Inborn errors of human IKAROS: LOF and GOF variants associated with primary immunodeficiency.
Kuehn HS et al.
Clinical and Experimental Immunology, 2023
MD-ALL: an Integrative Platform for Molecular Diagnosis of B-cell Acute Lymphoblastic Leukemia.
Gu Z et al.
Research Square, 2023
Integrative genomic analysis of childhood acute lymphoblastic leukaemia lacking a genetic biomarker in the UKALL2003 clinical trial.
Schwab C et al.
Leukemia, 2023
Whole genome sequencing provides comprehensive genetic testing in childhood B-cell acute lymphoblastic leukaemia.
Ryan SL et al.
Leukemia, 2023
Feasibility to use whole-genome sequencing as a sole diagnostic method to detect genomic aberrations in pediatric B-cell acute lymphoblastic leukemia.
Rezayee F et al.
Frontiers in Oncology, 2023
Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.
Cheng WY et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022
RaScALL: Rapid (Ra) screening (Sc) of RNA-seq data for prognostically significant genomic alterations in acute lymphoblastic leukaemia (ALL).
Rehn J et al.
Plos Genetics, 2022
Epigenetic activation of the FLT3 gene by ZNF384 fusion confers a therapeutic susceptibility in acute lymphoblastic leukemia.
Zhao X et al.
Nature Communications, 2022
The genomic landscape of pediatric acute lymphoblastic leukemia and precision medicine opportunities.
Tran TH et al.
Seminars in Cancer Biology, 2022