Associated Papers
IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura.
Spivak I et al.
Pediatric Blood & Cancer, 2026
IKAROS regulates human T cell phenotype at a thymic and postthymic level.
Stoddard J et al.
Jci Insight, 2025
Gain-of-function IKZF1 variants in humans cause immune dysregulation associated with abnormal T/B cell late differentiation.
Hoshino A et al.
Science Immunology, 2022
Identification and Validation of Ikaros (IKZF1) as a Cancer Driver Gene for Marek's Disease Virus-Induced Lymphomas.
Steep A et al.
Microorganisms, 2022
Case Report: A Highly Variable Clinical and Immunological Presentation of IKAROS Deficiency in a Single Family.
Kuijpers TW et al.
Frontiers in Immunology, 2022
Inborn errors of IKAROS and AIOLOS.
Yamashita M et al.
Current Opinion in Immunology, 2021
IKAROS-Associated Diseases in 2020: Genotypes, Phenotypes, and Outcomes in Primary Immune Deficiency/Inborn Errors of Immunity.
Kuehn HS et al.
Journal of Clinical Immunology, 2021
Clinical Courses of IKAROS and CTLA4 Deficiencies: A Systematic Literature Review and Retrospective Longitudinal Study.
Hoshino A et al.
Frontiers in Immunology, 2021
IKZF1 Loss-of-Function Variant Causes Autoimmunity and Severe Familial Antiphospholipid Syndrome.
Dieudonné Y et al.
Journal of Clinical Immunology, 2019
Assessing the Functional Relevance of Variants in the IKAROS Family Zinc Finger Protein 1 (IKZF1) in a Cohort of Patients With Primary Immunodeficiency.
Eskandarian Z et al.
Frontiers in Immunology, 2019
Familial Immune Thrombocytopenia Associated With a Novel Variant in IKZF1.
Sriaroon P et al.
Frontiers in Pediatrics, 2019
A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects.
Bogaert DJ et al.
The Journal of Allergy and Clinical Immunology, 2018
Evaluating the Genetics of Common Variable Immunodeficiency: Monogenetic Model and Beyond.
de Valles-Ibáñez G et al.
Frontiers in Immunology, 2018
Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations.
Hoshino A et al.
The Journal of Allergy and Clinical Immunology, 2017
Understanding the genetic and epigenetic basis of common variable immunodeficiency disorder through omics approaches.
Li J et al.
Biochimica Et Biophysica Acta, 2016
Loss of B Cells in Patients with Heterozygous Mutations in IKAROS.
Kuehn HS et al.
The New England Journal of Medicine, 2016
B-cell Deficiency: A De Novo IKZF1 Patient and Review of the Literature.
Chen QY et al.
Journal of Investigational Allergology & Clinical Immunology, 0