Associated Papers
IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura.
Spivak I et al.
Pediatric Blood & Cancer, 2026
IKAROS regulates human T cell phenotype at a thymic and postthymic level.
Stoddard J et al.
Jci Insight, 2025
A novel IKZF1 variant in a family with autosomal dominant CVID: A case for expanding exon coverage in inborn errors of immunity.
Stojkic I et al.
Clinical Immunology (orlando, Fla.), 2024
Can Ikaros mutation lead to intellectual disability?
Kose H et al.
Scandinavian Journal of Immunology, 2022
Gain-of-function IKZF1 variants in humans cause immune dysregulation associated with abnormal T/B cell late differentiation.
Hoshino A et al.
Science Immunology, 2022
Inborn errors of IKAROS and AIOLOS.
Yamashita M et al.
Current Opinion in Immunology, 2021
Germline IKAROS dimerization haploinsufficiency causes hematologic cytopenias and malignancies.
Kuehn HS et al.
Blood, 2021
IKZF1 Loss-of-Function Variant Causes Autoimmunity and Severe Familial Antiphospholipid Syndrome.
Dieudonné Y et al.
Journal of Clinical Immunology, 2019
Assessing the Functional Relevance of Variants in the IKAROS Family Zinc Finger Protein 1 (IKZF1) in a Cohort of Patients With Primary Immunodeficiency.
Eskandarian Z et al.
Frontiers in Immunology, 2019
Familial Immune Thrombocytopenia Associated With a Novel Variant in IKZF1.
Sriaroon P et al.
Frontiers in Pediatrics, 2019
Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency.
Boutboul D et al.
The Journal of Clinical Investigation, 2018
A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects.
Bogaert DJ et al.
The Journal of Allergy and Clinical Immunology, 2018
Evaluating the Genetics of Common Variable Immunodeficiency: Monogenetic Model and Beyond.
de Valles-Ibáñez G et al.
Frontiers in Immunology, 2018
Understanding the genetic and epigenetic basis of common variable immunodeficiency disorder through omics approaches.
Li J et al.
Biochimica Et Biophysica Acta, 2016
Normal hematologic parameters and fetal hemoglobin silencing with heterozygous IKZF1 mutations.
Abdulhay N et al.
Blood, 2016
Loss of B Cells in Patients with Heterozygous Mutations in IKAROS.
Kuehn HS et al.
The New England Journal of Medicine, 2016
B-cell Deficiency: A De Novo IKZF1 Patient and Review of the Literature.
Chen QY et al.
Journal of Investigational Allergology & Clinical Immunology, 0