Associated Papers
Tumefactive Demyelination in a Child With IKZF1 Gain-of-Function Variant.
Vuong T et al.
Pediatric Neurology, 2026
IKAROS regulates human T cell phenotype at a thymic and postthymic level.
Stoddard J et al.
Jci Insight, 2025
IgG4-Related Disease: Emerging Roles of Novel Genetic Variants, Immune Cell Subsets and Therapeutic Targets.
Tedesco L et al.
Allergy, 2025
IKZF1 and Ikaros Overexpression Results in Alopecia Areata-Like Phenotype in Mice.
Arakawa Y et al.
Experimental Dermatology, 2025
IgG4-related disease and B-cell malignancy due to an IKZF1 gain-of-function variant.
García-Solís B et al.
The Journal of Allergy and Clinical Immunology, 2024
Rare genetic variants provide a mechanistic basis for immune imbalance in IgG4-related disease.
Ciavatta DJ
The Journal of Clinical Investigation, 2024
Loss-of-phosphorylation of IKZF1 results in gain-of-function associated with immune dysregulation.
Hoshino A et al.
The Journal of Allergy and Clinical Immunology, 2024
IKZF1 and UBR4 gene variants drive autoimmunity and Th2 polarization in IgG4-related disease.
Liu Q et al.
The Journal of Clinical Investigation, 2024
IKAROS gain of function disease: Allogeneic hematopoietic cell transplantation experience and expanded clinical phenotypes.
Klangkalya N et al.
Clinical Immunology (orlando, Fla.), 2024
Pediatric Necrobiotic Xanthogranuloma as a Novel Phenotype of IKAROS Gain of Function.
Guess R et al.
Journal of Clinical Immunology, 2023
Inborn errors of human IKAROS: LOF and GOF variants associated with primary immunodeficiency.
Kuehn HS et al.
Clinical and Experimental Immunology, 2023
Gain-of-function IKZF1 variants in humans cause immune dysregulation associated with abnormal T/B cell late differentiation.
Hoshino A et al.
Science Immunology, 2022
Inborn errors of IKAROS and AIOLOS.
Yamashita M et al.
Current Opinion in Immunology, 2021
Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes.
Hadjadj J et al.
Blood, 2019
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