Varaico: Literature-Extracted Genetic Variants

Gene:IL10
Variant:p.K58N
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IL10

NM_000572.3:p.K58N

Associated Papers

Pro-inflammatory cytokine genetic variants show variable susceptibility to mild cognitive impairment, alzheimer's disease and frontotemporal dementia in South India.

Mallika AP et al.

Neurogenetics, 2025

Study of TNF-α, IFN-γ, IL-10, TGF-β and IL-6 Gene Polymorphisms in a Cohort of Professionals Who Worked in the First Pandemic Wave in the Brazilian Amazon.

Marcelino BDR et al.

Critical Reviews in Immunology, 2025

Interleukin-6 (-174G/C), Interleukin-1β (-511 C/T), and Apolipoprotein B-100 (2488 C/T) Gene Polymorphism in Pre-Eclampsia.

Najeeb MN et al.

Medicina (kaunas, Lithuania), 2024

Evaluation of the Impact of Some Single-Nucleotide Gene Polymorphisms on the Development of Adenomatous Polyps of the Colon in Patients with Irritable Bowel Syndrome.

Kyrian O et al.

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology, 2023

Association of IL6 and IL10 gene promotor polymorphisms with susceptibility to acute necrotizing encephalopathy.

Hoshino A et al.

Frontiers in Neuroscience, 2023

Distribution of 22 Single Nucleotide Polymorphisms in 13 Cytokine Genes in Malays, Chinese, and Indians in Peninsular Malaysia.

Hajar CGN et al.

Genetic Testing and Molecular Biomarkers, 2022

Evaluation of the relationship between IL-6 gene single nucleotide polymorphisms and the severity of COVID-19 in an Iranian population.

Falahi S et al.

Cytokine, 2022

The association of angiotensin-converting enzyme gene insertion/deletion polymorphism with bronchial asthma.

Krynytska I et al.

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego, 2021

Genetic Polymorphisms Associated with Rheumatoid Arthritis Development and Antirheumatic Therapy Response.

Mikhaylenko DS et al.

International Journal of Molecular Sciences, 2020

Influence of inflammasome NLRP3, and IL1B and IL2 gene polymorphisms in periodontitis susceptibility.

de Alencar JB et al.

Plos One, 2020

A meta-analysis on associations of IL-6 and IL-10 polymorphisms with susceptibility to ischemic stroke.

Chen M et al.

Journal of Neuroimmunology, 2019

Lack of association between single-nucleotide polymorphisms of pro- and anti-inflammatory cytokines and HTLV-1-associated myelopathy / tropical spastic paraparesis development in patients from Rio de Janeiro, Brazil.

Schor D et al.

Bmc Infectious Diseases, 2018

Viral and host factors associated with outcomes of hepatitis C virus infection (Review).

Yan Z et al.

Molecular Medicine Reports, 2017

Influence of cytokine gene polymorphisms on proinflammatory/anti-inflammatory cytokine imbalance in premature coronary artery disease.

Ansari WM et al.

Postgraduate Medical Journal, 2017

Host genetics role in the pathogenesis of periodontal disease and caries.

Nibali L et al.

Journal of Clinical Periodontology, 2017

Association between the IL-6 gene polymorphism and tuberculosis risk: a meta-analysis.

Wang H et al.

Infection and Drug Resistance, 2017

Polymorphisms of the interleukin 6 gene and additional gene-gene interaction contribute to cervical cancer susceptibility in Eastern Chinese women.

Pu X et al.

Archives of Gynecology and Obstetrics, 2016

Pro-inflammatory cytokines and their epistatic interactions in genetic susceptibility to schizophrenia.

Srinivas L et al.

Journal of Neuroinflammation, 2016

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IL-10 Polymorphisms and Tuberculosis Susceptibility: An Updated Meta-Analysis.

Ke Z et al.

Yonsei Medical Journal, 2015

The combination of tumour necrosis factor-α -308A and interleukin-10 -1082G gene polymorphisms and increased serum levels of related cytokines: susceptibility to vitiligo.

Aydıngöz IE et al.

Clinical and Experimental Dermatology, 2015

Association of IL-6 polymorphisms with hepatocellular carcinoma risk: evidences from a meta-analysis.

Liu Y et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

Interleukin-6 genotypes and serum levels in Chinese Hui population.

Gao SP et al.

International Journal of Clinical and Experimental Medicine, 2014

Cytokine gene polymorphisms and progression-free survival in classical Hodgkin lymphoma by EBV status: results from two independent cohorts.

Ghesquières H et al.

Cytokine, 2013

The association between interleukin-6 polymorphisms and systemic lupus erythematosus: a meta-analysis.

Lee YH et al.

Lupus, 2012

Cytokine gene haplotypes with a potential effect on susceptibility to malaria in sympatric ethnic groups in Mali.

Israelsson E et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2011

TGFB1 and IL8 gene polymorphisms and susceptibility to visceral leishmaniasis.

Frade AF et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2011

Cytokine gene polymorphism in idiopathic nephrotic syndrome children.

Jafar T et al.

Indian Journal of Clinical Biochemistry : Ijcb, 2011

Interleukin 6 promoter polymorphisms influence the outcome of chronic hepatitis C.

Cussigh A et al.

Immunogenetics, 2011

Functional inflammatory genotypes in ischemic stroke: could we use them to predict age of onset and long-term outcome?

Marousi S et al.

Stroke Research and Treatment, 2011

Differential combination of cytokine and interferon- γ +874 T/A polymorphisms determines disease severity in pulmonary tuberculosis.

Ansari A et al.

Plos One, 2011

Gene polymorphisms in chronic periodontitis.

Laine ML et al.

International Journal of Dentistry, 2010

Gene expression polymorphisms of interleukins-1 beta, -4, -6, -8, -10, and tumor necrosis factors-alpha, -beta: regression analysis of their effect upon oral squamous cell carcinoma.

Vairaktaris E et al.

Journal of Cancer Research and Clinical Oncology, 2008

Cytokine gene polymorphism and progression of renal and cardiovascular diseases.

Rao M et al.

Kidney International, 2007

IL6, aspirin, nonsteroidal anti-inflammatory drugs, and breast cancer risk in women living in the southwestern United States.

Slattery ML et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2007

Association of cytokine gene polymorphisms with malignant melanoma in Caucasian population.

Nikolova PN et al.

Cancer Immunology, Immunotherapy : Cii, 2007

Interleukin-6-related genotypes, body mass index, and risk of multiple myeloma and plasmacytoma.

Cozen W et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2006

Genetic predisposition and renal allograft failure: implication of non-HLA genetic variants.

Khan F et al.

Molecular Diagnosis & Therapy, 2006

Gene polymorphisms and transplantation.

Akalin E et al.

Current Opinion in Immunology, 2001

Gene polymorphism association studies in dialysis: the nutrition-inflammation axis.

Stenvinkel P et al.

Seminars in Dialysis, 0

Associations between TLR polymorphisms and systemic lupus erythematosus: a systematic review and meta-analysis.

Lee YH et al.

Clinical and Experimental Rheumatology, 0

Interleukin-6 polymorphisms and risk of coronary artery diseases in a Chinese population: A case-control study.

Hongmei Y et al.

Pakistan Journal of Medical Sciences, 0

IL6-174 G>C Polymorphism (rs1800795) Association with Late Effects of Low Dose Radiation Exposure in the Portuguese Tinea Capitis Cohort.

Boaventura P et al.

Plos One, 0

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