Associated Papers
C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease.
Landskron J et al.
Plos One, 2017
Overexpression of CD45RA isoforms in carriers of the C77G mutation leads to hyporeactivity of CD4+CD25highFoxp3+ regulatory T cells.
Pokoyski C et al.
Genes and Immunity, 2015
Altered CD45 isoform expression in C77G carriers influences cytokine responsiveness and adhesion properties of T cells.
Windhagen A et al.
Clinical and Experimental Immunology, 2007
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