Varaico: Literature-Extracted Genetic Variants

Gene:IL10RB
Variant:p.K47E
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IL10RB

NM_000628.5:p.K47E

Associated Papers

Stratified analyses refine association between TLR7 rare variants and severe COVID-19.

Boos J et al.

Hgg Advances, 2024

38944683 (PubMed )
Supplement: mmc4.xlsx › single_variants_p_lt_0.05

A novel biallelic 19-bp deletion in the IL10RB gene caused infant-onset inflammatory bowel disease in a consanguineous family: a molecular docking simulation study and literature review.

Motallebi F et al.

Molecular Biology Reports, 2024

The clinical, molecular, and therapeutic features of patients with IL10/IL10R deficiency: a systematic review.

Sharifinejad N et al.

Clinical and Experimental Immunology, 2022

Patient-specific genetic factors predict treatment failure in sofosbuvir-treated patients with chronic hepatitis C.

Loucks CM et al.

Liver International : Official Journal of the International Association for the Study of the Liver, 2022

Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry.

Bateman NW et al.

Iscience, 2022

35036865 (PubMed )
Supplement: mmc2.xlsx › SupplementalTable1A

The impact of IL-10 and CYP3A5 gene polymorphisms on dose-adjusted trough blood tacrolimus concentrations in early post-renal transplant recipients.

Chen Z et al.

Pharmacological Reports : Pr, 2021

A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.

Karakas Celik S et al.

International Journal of Immunogenetics, 2021

Susceptibility to Heart Defects in Down Syndrome Is Associated with Single Nucleotide Polymorphisms in HAS 21 Interferon Receptor Cluster and VEGFA Genes.

Balistreri CR et al.

Genes, 2020

Introducing the first whole genomes of nationals from the United Arab Emirates.

AlSafar HS et al.

Scientific Reports, 2019

31604968 (PubMed )
Supplement: 41598_2019_50876_MOESM1_ESM.xlsx › UAE_S001

Deep Resequencing of Ulcerative Colitis-Associated Genes Identifies Novel Variants in Candidate Genes in the Korean Population.

Moon CM et al.

Inflammatory Bowel Diseases, 2018

29733354 (PubMed )
Supplement: izy122_suppl_supporting_data.pdf

Polymorphism of IL-10 receptor β affects the prognosis of multiple myeloma patients treated with thalidomide and/or bortezomib.

Kasamatsu T et al.

Hematological Oncology, 2017

Investigation of Genetic Defects in Severe Combined Immunodeficiency Patients from Turkey by Targeted Sequencing.

Erman B et al.

Scandinavian Journal of Immunology, 2017

Genetic Contributions of Inflammation to Depression.

Barnes J et al.

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 2017

Very early-onset inflammatory bowel disease (IBD) in infancy is a different disease entity from adult-onset IBD; one form of interleukin-10 receptor mutations.

Shim JO et al.

Journal of Human Genetics, 2014

IL-10RB rs2834167 (A/G) polymorphism is associated with the susceptibility to systemic lupus erythematosus: evidence from a study in Chinese Han population.

Peng H et al.

Inflammation, 2013

Symptom clusters of pain, depressed mood, and fatigue in lung cancer: assessing the role of cytokine genes.

Reyes-Gibby CC et al.

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer, 2013

Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes.

Christodoulou K et al.

Gut, 2013

22543157 (PubMed )
Supplement: gutjnl-2011-301833-s1.pdf

Association of IFNAR2 and IL10RB genes in chronic hepatitis B virus infection.

Romporn S et al.

Tissue Antigens, 2013

Inherited variants in regulatory T cell genes and outcome of ovarian cancer.

Goode EL et al.

Plos One, 2013

23382860 (PubMed )
Supplement: pone.0053903.s002.xlsx › Supplemental_Table_2

Next-generation sequencing identifies transportin 3 as the causative gene for LGMD1F.

Torella A et al.

Plos One, 2013

23667635 (PubMed )
Supplement: pone.0063536.s006.xlsx › LGMD1F_HET_in_all

Inflammation profile of four early onset Crohn patients.

Marcuzzi A et al.

Gene, 2012

Innate immunity and non-Hodgkin's lymphoma (NHL) related genes in a nested case-control study for gastric cancer risk.

Park SK et al.

Plos One, 2012

23028900 (PubMed )
Supplement: pone.0045274.s001.xlsx › NHL

Viral hepatitis: human genes that limit infection.

Grünhage F et al.

Best Practice & Research. Clinical Gastroenterology, 2010

Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.

Hildebrandt MA et al.

Plos One, 2010

Structure and mechanism of receptor sharing by the IL-10R2 common chain.

Yoon SI et al.

Structure (london, England : 1993), 2010

Role of inflammation gene polymorphisms on pain severity in lung cancer patients.

Reyes-Gibby CC et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2009

Association study of IFNAR2 and IL10RB genes with the susceptibility and interferon response in HBV infection.

Gong QM et al.

Journal of Viral Hepatitis, 2009

IL10 and IL10 receptor gene variation and outcomes after unrelated and related hematopoietic cell transplantation.

Tseng LH et al.

Transplantation, 2009

Class II cytokine receptor gene cluster is a major locus for hepatitis B persistence.

Frodsham AJ et al.

Proceedings of the National Academy of Sciences of the United States of America, 2006

Interferon-alpha receptor-1 (IFNAR1) variants are associated with protection against cerebral malaria in the Gambia.

Aucan C et al.

Genes and Immunity, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."