Varaico: Literature-Extracted Genetic Variants

Gene:IL18
Variant:p.S46*
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IL18

NM_001562.4:p.S46*

Associated Papers

Genetic Factors Associated With Myocardial Infarction in Saudi Arabia.

Saeed A et al.

Journal of the Saudi Heart Association, 2025

Interleukin-18 Gene Polymorphisms and Rheumatoid Arthritis Susceptibility: An Umbrella Review of Meta-Analyses.

Chen Y et al.

Journal of Immunology Research, 2024

IL-18 and CD14 variants in chronic HBV predisposition: a case-control study with in silico analyses focused on transcription and splicing.

Sarhadi M et al.

Nucleosides, Nucleotides & Nucleic Acids, 2024

Association of Single Nucleotide Polymorphisms of Cytokine Genes with Depression, Schizophrenia and Bipolar Disorder.

Mikhalitskaya EV et al.

Genes, 2023

Association between IL-18 gene polymorphisms and Hashimoto thyroiditis.

Karakaya D et al.

Molecular Biology Reports, 2021

Inflammasome genetics and complex diseases: a comprehensive review.

Fernandes FP et al.

European Journal of Human Genetics : Ejhg, 2020

32499599 (PubMed )
Supplement: 41431_2020_631_MOESM3_ESM.docx

Polymorphism in the Promoter Region of the IL18 Gene and the Association With Severity on Paracoccidioidomycosis.

Sato PK et al.

Frontiers in Immunology, 2020

33117339 (PubMed )
Supplement: Data_Sheet_1.PDF

A Specific IL6 Polymorphic Genotype Modulates the Risk of Trypanosoma cruzi Parasitemia While IL18, IL17A, and IL1B Variant Profiles and HIV Infection Protect Against Cardiomyopathy in Chagas Disease.

Gomes Dos Santos A et al.

Frontiers in Immunology, 2020

Association between interleukin-18 (137G/C and 607C/A) gene polymorphisms and risk of ischemic stroke: a meta-analysis.

Zhou L et al.

Neuroreport, 2019

Genetic association of interleukin 18 (-607C/A, rs1946518) single nucleotide polymorphism with asthmatic children, disease severity and total IgE serum level.

Ezzat DA et al.

Central-european Journal of Immunology, 2019

Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study.

Hernandez-Fuentes MP et al.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2018

29392897 (PubMed )
Supplement: AJT-18-1370-s002.xlsx › Data

Association between donor and recipient Interleukin-18 gene polymorphisms and the risk of infection after liver transplantation.

Shi BJ et al.

Clinical and Investigative Medicine. Medecine Clinique Et Experimentale, 2017

Interleukin-18 (rs187238) and glucose transporter 4 (rs5435) polymorphisms in Euro-Brazilians with type 1 diabetes.

Al-Lahham Y et al.

Genetics and Molecular Research : Gmr, 2017

Assessment of IL-18 Serum Level and Its Promoter Polymorphisms in the Saudi Coronary Artery Disease (CAD) Patients.

Jabir NR et al.

Journal of Cellular Biochemistry, 2017

IL-18 gene polymorphism in patients with visceral leishmaniasis in East Azarbaijan, Iran.

Ahmadpour E et al.

Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology, 2016

The association of IL-18 gene promoter polymorphisms and the levels of serum IL-18 on the risk of multiple sclerosis.

Orhan G et al.

Clinical Neurology and Neurosurgery, 2016

Association of interleukin 18-607A/C and -137C/G polymorphisms with oxidative stress in renal transplant recipients.

Davran F et al.

Renal Failure, 2016

Association of IL-18 polymorphisms with rheumatoid arthritis: a meta-analysis.

Li LL et al.

Genetics and Molecular Research : Gmr, 2016

IL-18, TNF, and IFN-γ alleles and genotypes are associated with susceptibility to chronic hepatitis B infection and severity of liver injury.

Ferreira Sda C et al.

Journal of Medical Virology, 2015

Ethnicity-stratified analysis of the association between IL-18 polymorphisms and systemic lupus erythematosus in a European population: a meta-analysis.

Guo BR et al.

Archives of Dermatological Research, 2015

IL-18 polymorphisms in hepatitis B virus related liver disease.

Karra VK et al.

Cytokine, 2015

Interleukin-18 gene promoter polymorphisms and celiac disease in Italian patients.

Zupin L et al.

Molecular Biology Reports, 2015

Role of IL-18 Gene Promoter Polymorphisms, Serum IL-18 Levels, and Risk of Hepatitis B Virus-related Liver Disease in the Guangxi Zhuang Population: a Retrospective Case-Control Study.

Lu Y et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2015

Association between Genetic Variants and Diabetes Mellitus in Iranian Populations: A Systematic Review of Observational Studies.

Khodaeian M et al.

Journal of Diabetes Research, 2015

Association of IL-18 promoter gene polymorphisms with rheumatoid arthritis: a meta-analysis.

Cai LP et al.

Molecular Biology Reports, 2014

Interleukin-18 -607C/A gene polymorphism in Egyptian asthmatic children.

Shaaban HH et al.

Molecular Diagnosis & Therapy, 2014

Absence of association of interleukin-18 gene polymorphisms with primary immune thrombocytopenia in a Chinese Han population.

Li H et al.

Dna and Cell Biology, 2014

Interleukin 18 gene promoter polymorphisms and susceptibility to chronic hepatitis B infection: a review study.

Motavaf M et al.

Hepatitis Monthly, 2014

Genetic polymorphisms of Interleukin-18 are not associated with allograft function in kidney transplant recipients.

do Nascimento WG et al.

Genetics and Molecular Biology, 2014

Association of the interleukin-18 -137 C/G, -607 A/C polymorphisms with type 1 diabetes: A meta-analysis.

Li J et al.

Biomedical Reports, 2014

Polymorphism of the IL-18 and CD40 genes and Liver Transplant Outcome in Iranian Patients.

Hejr S et al.

International Journal of Organ Transplantation Medicine, 2014

The association of interleukin-18 promoter polymorphisms and serum levels with duodenal ulcer, and their correlations with bacterial CagA and VacA virulence factors.

Rezaeifar A et al.

Scandinavian Journal of Infectious Diseases, 2013

Association between interleukin-18 polymorphisms and systemic lupus erythematosus: a meta-analysis.

Song GG et al.

Molecular Biology Reports, 2013

Interleukin-18 and interferon-gamma polymorphisms are implicated on proviral load and susceptibility to human T-lymphotropic virus type 1 infection.

Rocha-Júnior MC et al.

Tissue Antigens, 2012

Interleukin-18 promoter polymorphism and asthma risk: a meta-analysis.

Ma Y et al.

Molecular Biology Reports, 2012

Interleukin 4 and STAT6 gene polymorphisms are associated with systemic lupus erythematosus in Chinese patients.

Yu HH et al.

Lupus, 2010

Haplotype analysis of the interleukin-18 gene in Czech patients with allergic disorders.

Izakovicova Holla L et al.

Human Immunology, 2010

Impact of interleukin-18 polymorphisms-607 and -137 on clinical characteristics of renal cell carcinoma patients.

Sáenz-López P et al.

Human Immunology, 2010

Association of single nucleotide polymorphism of interleukin-18 with atopic dermatitis.

Trzeciak M et al.

Journal of the European Academy of Dermatology and Venereology : Jeadv, 2010

Interleukin-18 gene 105A/C genetic polymorphism is associated with the susceptibility of Kawasaki disease.

Chen SY et al.

Journal of Clinical Laboratory Analysis, 2009

Influence of interleukin 18 promoter polymorphisms in susceptibility to Kawasaki disease in Taiwan.

Hsueh KC et al.

The Journal of Rheumatology, 2008

[Correlation of serum IL-18 level and IL-18 gene promoter polymorphisms to the risk of cervical cancer].

Qi T et al.

Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University, 2008

Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: the Helsinki Sudden Death Study.

Hernesniemi JA et al.

Atherosclerosis, 2008

Interleukin gene polymorphisms in age-related macular degeneration.

Tsai YY et al.

Investigative Ophthalmology & Visual Science, 2008

Interleukin (IL)-18 polymorphism 133C/G is associated with severe respiratory syncytial virus infection.

Puthothu B et al.

The Pediatric Infectious Disease Journal, 2007

Polymorphism of interleukin-18 promoter influences the onset of kidney graft function after transplantation.

Kolesar L et al.

Tissue Antigens, 2007

Disease association of the interleukin-18 promoter polymorphisms in Taiwan Chinese systemic lupus erythematosus patients.

Lin YJ et al.

Genes and Immunity, 2007

IL-18 gene promoter -137C/G and -607C/A polymorphisms in Chinese Han children with type 1 diabetes mellitus.

Dong GP et al.

International Journal of Immunogenetics, 2007

Interleukin-18 promoter polymorphisms in patients with Behçet's disease.

Lee YJ et al.

Human Immunology, 2006

Disease association of two distinct interleukin-18 promoter polymorphisms in Caucasian rheumatoid arthritis patients.

Gracie JA et al.

Genes and Immunity, 2005

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