Varaico: Literature-Extracted Genetic Variants

Gene:IL2
Variant:p.R103K
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IL2

NM_000586.4:p.R103K

Associated Papers

High nasopharyngeal and serum IL-6 levels and the - 573G > C polymorphism (rs1800796) are linked with the risk of severe COVID-19 in a Mexican population: a case‒control study.

Torres-Poveda K et al.

Bmc Infectious Diseases, 2025

The Association of HHV-6 and the TNF-α (-308G/A) Promotor with Major Depressive Disorder Patients and Healthy Controls in Thailand.

Sumala S et al.

Viruses, 2023

Association between Tumor Necrosis factor-Alpha(TNF-a) polymorphisms and Schizophrenia: an updated meta-analysis.

He S et al.

International Journal of Psychiatry in Clinical Practice, 2022

Interlukin-27 rs153109 polymorphism confers the susceptibility and prognosis of aplastic anemia in Chinese population.

Yu W et al.

International Journal of Laboratory Hematology, 2022

Genetic variations related to inflammation in suicidal ideation and behavior: A systematic review.

Tamimou R et al.

Frontiers in Psychiatry, 2022

Impact of TNF-α Gene Polymorphisms on Pancreatic and Non-Small Cell Lung Cancer-Induced Cachexia in Adult Egyptian Patients: A Focus on Pathogenic Trajectories.

Yehia R et al.

Frontiers in Oncology, 2021

Association of single nucleotide polymorphisms in TNF-α (-308G/A and -238G/A) to dengue: Case-control and meta-analysis study.

Santos NCD et al.

Cytokine, 2020

Associations of the -238(G/A) and -308(G/A) TNF-α Promoter Polymorphisms and TNF-α Serum Levels with the Susceptibility to Gastric Precancerous Lesions and Gastric Cancer Related to Helicobacter pylori Infection in a Moroccan Population.

Bounder G et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2020

Association between polymorphic markers human leucocyte antigen-G and tumour necrosis factor alpha and susceptibility to recurrent miscarriages among Bulgarian women.

Levkova M et al.

Turkish Journal of Obstetrics and Gynecology, 2020

Association Analysis of Tumor Necrosis Factor Alpha Promoter Polymorphisms and Vitiligo Susceptibility in South Indian Tamils.

Rajendiran KS et al.

Dermatology (basel, Switzerland), 2020

TNF-α polymorphisms affect persistence and progression of HBV infection.

Woziwodzka A et al.

Molecular Genetics & Genomic Medicine, 2019

Genetic polymorphisms in tumor necrosis factor alpha and interleukin-10 are associated with an increased risk of cervical cancer.

Du GH et al.

International Immunopharmacology, 2019

Lack of association between single-nucleotide polymorphisms of pro- and anti-inflammatory cytokines and HTLV-1-associated myelopathy / tropical spastic paraparesis development in patients from Rio de Janeiro, Brazil.

Schor D et al.

Bmc Infectious Diseases, 2018

Association between cytokine genes polymorphisms and type 1 diabetes: a case-control study on Saudi population.

Allam G et al.

Immunological Investigations, 2018

The impact of host's genetic susceptibility on Helicobacter pylori infection in children.

Mărginean MO et al.

Medicine, 2017

The influence of TNF alpha -308 G/A polymorphism on oxidative stress in patients with chronic lymphocytic leukemia.

Jevtovic-Stoimenov T et al.

Leukemia Research, 2017

Association of promoter polymorphism -857C/T (rs1799724) in tumor necrosis factor gene with intracerebral hemorrhage in Korean males.

Park HJ et al.

Neurological Research, 2017

The role of polymorphism of interleukin-2, -10, -13 and TNF-α genes in cutaneous T-cell lymphoma pathogenesis.

Nedoszytko B et al.

Postepy Dermatologii I Alergologii, 2016

The combination of tumour necrosis factor-α -308A and interleukin-10 -1082G gene polymorphisms and increased serum levels of related cytokines: susceptibility to vitiligo.

Aydıngöz IE et al.

Clinical and Experimental Dermatology, 2015

Polymorphisms in the IFNγ, IL-10, and TGFβ genes may be associated with HIV-1 infection.

Freitas FB et al.

Disease Markers, 2015

Inflammation-related cytokine gene polymorphisms in Behçet's disease.

Al-Okaily F et al.

Journal of Inflammation Research, 2015

TNF-α promoter single nucleotide polymorphisms and haplotypes associate with susceptibility of immune thrombocytopenia in Chinese adults.

Wang N et al.

Human Immunology, 2014

Polymorphisms in the TNF-α and IL-10 gene promoters and risk of psoriasis and correlation with disease severity.

Karam RA et al.

Cytokine, 2014

Cytokine gene polymorphisms and progression-free survival in classical Hodgkin lymphoma by EBV status: results from two independent cohorts.

Ghesquières H et al.

Cytokine, 2013

The role of TNF-α and PAI-1 gene polymorphisms in familial Mediterranean fever.

Dundar M et al.

Modern Rheumatology, 2013

Relationship between vitamin D receptor gene polymorphisms and migraine without aura in an Iranian population.

Motaghi M et al.

Biomed Research International, 2013

Analysis of polymorphisms of TNF-α, LT-α, IL-10, IL-12 and CTLA-4 in patients with warm autoimmune haemolytic anaemia.

D'Abronzo LS et al.

International Journal of Laboratory Hematology, 2012

TNF-α Polymorphisms in Juvenile Idiopathic Arthritis: Which Potential Clinical Implications?

Scardapane A et al.

International Journal of Rheumatology, 2012

The promoter -1031(T/C) polymorphism in tumor necrosis factor-alpha associated with polycystic ovary syndrome.

Yun JH et al.

Reproductive Biology and Endocrinology : Rb&e, 2011

Genetic variations in tumor necrosis factor alpha, interleukin-10 genes, and migraine susceptibility.

Ates O et al.

Pain Medicine (malden, Mass.), 2011

Association between interleukin-10 gene polymorphism -592 (A/C) and peritoneal transport in patients undergoing peritoneal dialysis.

Lee YT et al.

Nephrology (carlton, Vic.), 2011

Association of IL1A, IL1B, ILRN, IL6, IL10 and TNF-α polymorphisms with risk and clinical course of multiple sclerosis in a Polish population.

Mirowska-Guzel D et al.

Journal of Neuroimmunology, 2011

IL-4 and TNF-α polymorphisms are associated with risk of multiple superficial tumors or carcinoma in situ development.

Lima L et al.

Urologia Internationalis, 2011

Cytokine genetic polymorphisms and susceptibility to Kawasaki disease in Taiwanese children.

Weng KP et al.

Circulation Journal : Official Journal of the Japanese Circulation Society, 2010

Analyses of functional IL10 and TNF-α genotypes in Behçet's syndrome.

Ateş O et al.

Molecular Biology Reports, 2010

Tumor necrosis factor-alpha gene -308 G/A polymorphism modulates the relationship between dietary fat intake, serum lipids, and obesity risk in black South African women.

Joffe YT et al.

The Journal of Nutrition, 2010

Cytokine gene polymorphisms in preeclampsia and eclampsia.

de Lima TH et al.

Hypertension Research : Official Journal of the Japanese Society of Hypertension, 2009

Tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphisms in Turkish rheumatoid arthritis patients.

Ates O et al.

Clinical Rheumatology, 2008

Association between cytokine gene polymorphisms and outcomes in renal transplantation: a meta-analysis of individual patient data.

Thakkinstian A et al.

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association, 2008

Relationship between periodontal findings and the TNF-alpha Gene 1031T/C polymorphism in Turkish patients with Behçet's disease.

Akman A et al.

Journal of the European Academy of Dermatology and Venereology : Jeadv, 2008

Interleukin-10 and tumor necrosis factor-alpha gene polymorphisms in tuberculosis.

Ates O et al.

Journal of Clinical Immunology, 2008

The polymorphism -863C/A in tumour necrosis factor-alpha gene contributes an independent association to gout.

Chang SJ et al.

Rheumatology (oxford, England), 2007

Cytokine gene polymorphisms and breast cancer susceptibility.

Scola L et al.

Annals of the New York Academy of Sciences, 2006

Association of TNF-alpha promoter polymorphisms with the outcomes of hepatitis B virus infection in Chinese Han population.

Du T et al.

Journal of Viral Hepatitis, 2006

Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-alpha gene promoter polymorphisms.

Cheong JY et al.

Journal of Gastroenterology and Hepatology, 2006

The association of cytokine gene polymorphisms with febrile non-hemolytic transfusion reaction in multitransfused patients.

Addas-Carvalho M et al.

Transfusion Medicine (oxford, England), 2006

Cytokine gene polymorphisms and risks of acute rejection and delayed graft function after kidney transplantation.

Alakulppi NS et al.

Transplantation, 2004

Polymorphisms in cytokines and growth factor genes and their association with acute rejection and recurrence of hepatitis C virus disease in liver transplantation.

Mas VR et al.

Clinical Genetics, 2004

Angiotensin-converting enzyme gene polymorphisms in patients with pulmonary sarcoidosis: impact on disease severity.

Schürmann M

American Journal of Pharmacogenomics : Genomics-related Research in Drug Development and Clinical Practice, 2003

TNF-308A and HLA-DR3 alleles contribute independently to susceptibility to systemic lupus erythematosus.

Rood MJ et al.

Arthritis and Rheumatism, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."