Varaico: Literature-Extracted Genetic Variants

Gene:IL2RA
Variant:p.L63P
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IL2RA

NM_000417.3:p.L63P

Associated Papers

Genomic Landscape of Susceptibility to Severe COVID-19 in the Slovenian Population.

Kovanda A et al.

International Journal of Molecular Sciences, 2024

39062917 (PubMed )
Supplement: ijms-25-07674-s001.zip › Supplementary_table_3.xlsx › ACMG_classified_variants

Interplay between single resistance-associated mutations in the HIV-1 protease and viral infectivity, protease activity, and inhibitor sensitivity.

Henderson GJ et al.

Antimicrobial Agents and Chemotherapy, 2012

Atazanavir signature I50L resistance substitution accounts for unique phenotype of increased susceptibility to other protease inhibitors in a variety of human immunodeficiency virus type 1 genetic backbones.

Weinheimer S et al.

Antimicrobial Agents and Chemotherapy, 2005

Novel human immunodeficiency virus type 1 protease mutations potentially involved in resistance to protease inhibitors.

Svicher V et al.

Antimicrobial Agents and Chemotherapy, 2005

Nelfinavir-resistant, amprenavir-hypersusceptible strains of human immunodeficiency virus type 1 carrying an N88S mutation in protease have reduced infectivity, reduced replication capacity, and reduced fitness and process the Gag polyprotein precursor aberrantly.

Resch W et al.

Journal of Virology, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."