Varaico: Literature-Extracted Genetic Variants

Gene:IL2RG
Variant:p.C182Y
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IL2RG

NM_000206.3:p.C182Y

Associated Papers

IL-21 is the primary common γ chain-binding cytokine required for human B-cell differentiation in vivo.

Recher M et al.

Blood, 2011

Long-term persistence of a polyclonal T cell repertoire after gene therapy for X-linked severe combined immunodeficiency.

Gaspar HB et al.

Science Translational Medicine, 2011

Clinical and immunologic consequences of a somatic reversion in a patient with X-linked severe combined immunodeficiency.

Speckmann C et al.

Blood, 2008

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients.

Howe SJ et al.

The Journal of Clinical Investigation, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."