Associated Papers
KPT330 promotes the sensitivity of glioblastoma to olaparib by retaining SQSTM1 in the nucleus and disrupting lysosomal function.
Wang LH et al.
Autophagy, 2024
NAD+ regulates nucleotide metabolism and genomic DNA replication.
Munk SHN et al.
Nature Cell Biology, 2023
37957325 (PubMed )
Supplement: 41556_2023_1280_MOESM1_ESM.pdf
Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis.
Tan IL et al.
Cell Reports, 2023
Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.
Jambeau M et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022
36454749 (PubMed )
Supplement: pnas.2123487119.sapp.pdf
Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.
Amen AM et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021
33758097 (PubMed )
Supplement: pnas.2008772118.sapp.pdf
Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.
Braun CJ et al.
Cancer Cell, 2017
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