Varaico: Literature-Extracted Genetic Variants

Gene:IL36RN
Variant:p.N47S
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IL36RN

NM_012275.3:p.N47S

Associated Papers

Epidermal second-hit mutation in MVK gene associated with linear porokeratosis.

Zhao A et al.

Genes & Diseases, 2025

39386107 (PubMed )
Supplement: mmc2.xlsx › standard

IL-36RN gene: key insights into its role in pediatric pustular psoriasis pathogenesis and treatment.

Wang Y et al.

Frontiers in Pediatrics, 2025

IL36RN mutations in Chinese patients with acute generalized exanthematous pustulosis.

Li Z et al.

International Journal of Dermatology, 2024

Whole exome sequencing identifies genetic markers of enterovirus susceptibility in East Asians.

Sung CC et al.

Frontiers in Microbiology, 2024

39234544 (PubMed )
Supplement: Data_Sheet_2.xlsx › worksheet

In Silico and In Vitro Analysis of IL36RN Alterations Reveals Critical Residues for the Function of the Interleukin-36 Receptor Complex.

Hassi NK et al.

The Journal of Investigative Dermatology, 2023

Newly revealed variants of SERPINA3 in generalized pustular psoriasis attenuate inhibition of ACT on cathepsin G.

Liu Y et al.

Journal of Human Genetics, 2023

Prevalence, comorbidities and mortality of generalized pustular psoriasis: A literature review.

Prinz JC et al.

Journal of the European Academy of Dermatology and Venereology : Jeadv, 2023

Different Clinical Features of Pediatric Generalized Pustular Psoriasis in Patients with or without IL36RN Variants.

Wang Z et al.

Dermatology (basel, Switzerland), 2023

An update on genetic basis of generalized pustular psoriasis (Review).

Zhou J et al.

International Journal of Molecular Medicine, 2021

Acute generalized exanthematous pustulosis triggered by acetaminophen in an IL36RN variant heterozygote.

Murase C et al.

The Journal of Dermatology, 2021

Association between mutation of interleukin 36 receptor antagonist and generalized pustular psoriasis: A PRISMA-compliant systematic review and meta-analysis.

Liu ZJ et al.

Medicine, 2020

Clinical characteristics, genetics, comorbidities and treatment of palmoplantar pustulosis: A retrospective analysis of 66 cases in a single center in Taiwan.

Huang CM et al.

The Journal of Dermatology, 2020

A Vietnamese human genetic variation database.

Le VS et al.

Human Mutation, 2019

Genetic polymorphism of IL36RN in Han patients with generalized pustular psoriasis in Sichuan region of China: A case-control study.

Li Z et al.

Medicine, 2018

Codeine-induced acute generalized exanthematous pustulosis without IL36RN mutations.

Chadli Z et al.

Pharmacogenomics, 2018

[Genetic Polymorphism of IL36RN in Han Patients with Generalized Pustular Psoriasis Alone in Sichuan Region].

Li ZT et al.

Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition, 2018

Clinical profiles of pediatric patients with GPP alone and with different IL36RN genotypes.

Wang Y et al.

Journal of Dermatological Science, 2017

Mutation analysis of IL36RN gene in Japanese patients with palmoplantar pustulosis.

Takahashi T et al.

The Journal of Dermatology, 2017

Correlation of IL36RN mutation with different clinical features of pustular psoriasis in Chinese patients.

Wang TS et al.

Archives of Dermatological Research, 2016

Novel IL36RN gene mutation revealed by analysis of 8 Japanese patients with generalized pustular psoriasis.

Hayashi M et al.

Journal of Dermatological Science, 2014

Molecular determinants of agonist and antagonist signaling through the IL-36 receptor.

Günther S et al.

Journal of Immunology (baltimore, Md. : 1950), 2014

Prevalent and rare mutations in IL-36RN gene in Chinese patients with generalized pustular psoriasis and psoriasis vulgaris.

Li M et al.

The Journal of Investigative Dermatology, 2013

Lack of association between mutation in IL36RN and palmoplantar pustular psoriasis in Chinese patients.

Xiaoling Y et al.

Anais Brasileiros De Dermatologia, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."