Varaico: Literature-Extracted Genetic Variants

Gene:IL4R
Variant:p.C431R
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IL4R

NM_000418.4:p.C431R

Associated Papers

Nonsteroidal anti-inflammatory drug-induced acute urticaria/angioedema associated with atopy-related genes' genetic variants.

Jiménez-Sánchez IM et al.

The Journal of Allergy and Clinical Immunology, 2026

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc5.xlsx › Sheet1

Exploring multi-omics and clinical characteristics linked to accelerated biological aging in Asian women of reproductive age: insights from the S-PRESTO study.

Chen L et al.

Genome Medicine, 2024

39516835 (PubMed )
Supplement: 13073_2024_1403_MOESM3_ESM.xlsx › Table_S4B

Relevance of Coding Variation in FLG And DOCK8 in Finnish Pediatric Patients with Early-Onset Moderate-To-Severe Atopic Dermatitis.

Perälä M et al.

Jid Innovations : Skin Science From Molecules to Population Health, 2023

37533579 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_S1

Genetic Factors in Familial Manifestation of Primary Mediastinal Large B-Cell Lymphoma over Two Generations.

Juskevicius D et al.

Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology, 2023

Comprehensive investigating of cytokine and receptor related genes variants in patients with chronic hepatitis B virus infection.

Yu F et al.

Cytokine, 2018

Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.

Lonjou C et al.

Bmc Cancer, 2017

28499365 (PubMed )
Supplement: 12885_2017_3314_MOESM1_ESM.xls › SupplTableS1.xls

Palm dermatoglyphs and interleukin-4 receptor polymorphisms in asthma.

Sun L et al.

Biomedical Reports, 2017

Genetic analysis of asthma exacerbations.

Anderson WH et al.

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, 2013

Interleukin 4, interleukin 4 receptor-α and interleukin 10 gene polymorphisms in Chagas disease.

Flórez O et al.

Parasite Immunology, 2011

Allergic bronchopulmonary aspergillosis in asthma and cystic fibrosis.

Knutsen AP et al.

Clinical & Developmental Immunology, 2011

Immunopathology and immunogenetics of allergic bronchopulmonary aspergillosis.

Knutsen AP

Journal of Allergy, 2011

Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets.

Isokpehi RD et al.

Bioinformatics and Biology Insights, 2010

20981267 (PubMed )
Supplement: BBI-4-supplementary.xls › SNPs3D_-_Substitutions_from_Cys

Association of IL-4RA single nucleotide polymorphisms, HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthma.

Knutsen AP et al.

Clinical and Molecular Allergy : Cma, 2010

Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohort.

Biagini Myers JM et al.

The Journal of Investigative Dermatology, 2010

Association analysis of SNPs in the IL4R locus with type I diabetes.

Erlich HA et al.

Genes and Immunity, 2009

Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma.

Tachdjian R et al.

The Journal of Experimental Medicine, 2009

Cytokine and cytokine receptor single-nucleotide polymorphisms predict risk for non-small cell lung cancer among women.

Van Dyke AL et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2009

Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.

Van Dyke AL et al.

Cytokine, 2009

Association of IL4R gene polymorphisms with asthma in Chinese populations.

Zhang H et al.

Human Mutation, 2007

Interleukin-4 and interleukin-4 receptor polymorphisms and colorectal cancer risk.

Landi S et al.

European Journal of Cancer (oxford, England : 1990), 2007

Serum IgE, tumor epidermal growth factor receptor expression, and inherited polymorphisms associated with glioma survival.

Wrensch M et al.

Cancer Research, 2006

Effects of common atopy-associated amino acid substitutions in the IL-4 receptor alpha chain on IL-4 induced phenotypes.

Franjkovic I et al.

Immunogenetics, 2005

Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer.

Landi S et al.

Cancer Research, 2003

V75R576 IL-4 receptor alpha is associated with allergic asthma and enhanced IL-4 receptor function.

Risma KA et al.

Journal of Immunology (baltimore, Md. : 1950), 2002

Analysis of single-nucleotide polymorphisms in the interleukin-4 receptor gene for association with inflammatory bowel disease.

Olavesen MG et al.

Immunogenetics, 2000

The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction.

Kruse S et al.

Immunology, 1999

Abstracts from the eighth annual meeting of the international genetic epidemiology society

Wang HM et al.

Genetic Epidemiology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."