Varaico: Literature-Extracted Genetic Variants

Gene:IL4R
Variant:p.Y713F
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IL4R

NM_000418.4:p.Y713F

Associated Papers

An atopy-associated polymorphism in the ectodomain of the IL-4R(alpha) chain (V50) regulates the persistence of STAT6 phosphorylation.

Ford AQ et al.

Journal of Immunology (baltimore, Md. : 1950), 2009

Regulation of the dephosphorylation of Stat6. Participation of Tyr-713 in the interleukin-4 receptor alpha, the tyrosine phosphatase SHP-1, and the proteasome.

Hanson EM et al.

The Journal of Biological Chemistry, 2003

Immunoreceptor tyrosine-based inhibitory motif of the IL-4 receptor associates with SH2-containing phosphatases and regulates IL-4-induced proliferation.

Kashiwada M et al.

Journal of Immunology (baltimore, Md. : 1950), 2001

Cutting edge: effects of an allergy-associated mutation in the human IL-4R alpha (Q576R) on human IL-4-induced signal transduction.

Wang HY et al.

Journal of Immunology (baltimore, Md. : 1950), 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."