Varaico: Literature-Extracted Genetic Variants

Gene:IL6
Variant:p.R58R
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IL6

NM_000600.5:p.R58R

Associated Papers

Pro-inflammatory Immune Dysregulation and Genetic Susceptibility in Iraqi Children with Autism: a Tetra-Primer ARMS-PCR Investigation of Interleukin Polymorphisms.

Hoidy WH et al.

Journal of Molecular Neuroscience : Mn, 2026

From Bench to Bedside: Personalized Genomics in the Diagnosis and Treatment of Osteomyelitis.

Hoveidaei AH et al.

Antibiotics (basel, Switzerland), 2026

The effect of inflammatory factors on unstable angina risk, from the gene level.

Lou J et al.

Scientific Reports, 2026

IL10 rs1800896 Genetic Variant Predicts Biochemical Remission in Inflammatory Bowel Disease Patients Undergoing Biologic Therapy.

Falzone MH et al.

Immunology, 2026

Genetic polymorphisms in headache attributed to temporomandibular disorder: A case-control study.

Campello CP et al.

Archives of Oral Biology, 2026

Evaluating Associations Between Ankylosing Spondylitis, Torque Teno Virus and Polymorphisms in Interleukin 6 and Vitamin D Receptor Genes.

Cimponeriu D et al.

International Journal of Immunogenetics, 2026

Exploratory Analysis of TLR2, TLR4, Interleukin 6 and Interleukin 10 Gene Polymorphisms in Relation to Clinical Early-Onset Sepsis in Preterm Neonates: A Single-Center Study.

Baizat M et al.

Life (basel, Switzerland), 2026

Unfolding the enigma of familial Hodgkin lymphoma: Current insights.

Roganovic J et al.

World Journal of Clinical Cases, 2026

Polymorphisms in TLR4 and IL6 and their association with obesity and insulin resistance in a Venezuelan population.

Hernández Osorio S et al.

Endocrinologia, Diabetes Y Nutricion, 2026

Genetic and Epigenetic Components in the Pathogenesis of Adenomyosis and Endometriosis in Adolescents.

Palumbo M et al.

Biomedicines, 2025

Association between interleukin-6 promoter polymorphisms and osteoporosis in javanese postmenopausal women.

Utami SL et al.

European Cytokine Network, 2025

Genetic and epigenetic contributors and mimickers of phenotypic hypoxic-ischemic encephalopathy (HIE).

Mietzsch U et al.

Seminars in Perinatology, 2025

Association between IL-6 gene polymorphisms and susceptibility to Parkinson's disease.

Gao J et al.

Annals of Human Biology, 2025

IL-6 and TNF variants as potential determinants of perianal disease in Crohn's patients: a pilot study.

Cusato J et al.

Cytokine, 2025

Genetic polymorphisms and diabetic foot ulcer susceptibility: a systematic review and meta-analysis of Indian populations.

Kumar YS et al.

Journal of Diabetes and Metabolic Disorders, 2025

Association of polycystic ovarian syndrome with inflammatory single nucleotide polymorphism for IL-1 & IL-6 genes: A case-control study.

Benjamin JJ et al.

The Indian Journal of Medical Research, 2025

Exploring the Link Between IL-6 rs1800795 G > C SNP and the Severity of Epstein-Barr Virus-Associated Multiple Sclerosis: Potential Impact on Cognitive Impairment.

Hassan TM et al.

Molecular Neurobiology, 2025

The role of IL1β, IL6, and IL10 genetic variants in susceptibility to recurrent aphthous stomatitis: A systematic review and bioinformatics approach.

Surboyo MDC et al.

Archives of Oral Biology, 2025

Impact of IL-6 Promotor AnTn Polymorphism on Blood IL-6 Levels and Pregnancy Outcome in Toxoplasma gondii Infected Women.

Khan MB et al.

Parasite Immunology, 2025

TNF-α 308 (rs1800629) and INF-γ +874 polymorphisms in dengue progression: genotype-specific trends amidst allelic non-association in West Africa.

Tassembedo F et al.

Cellular and Molecular Biology (noisy-le-grand, France), 2025

Interleukin gene polymorphisms (IL1B, IL6, IL10, IL16, IL28B) increase prostate cancer risk and associate with aggressive disease features in Iraqi men: A case-control study.

Hoidy WH et al.

Cancer Epidemiology, 2025

The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence.

Oyovwi MO et al.

Brain and Behavior, 2025

The Polymorphism of Metabolic and Immune Mechanisms Controlling Genes in Type 2 Diabetes Mellitus.

Shramko I et al.

Genes, 2025

Genetic polymorphisms associated with periodontitis in Japanese populations: A comprehensive review of pathways, interactions, and clinical implications.

Ferrara E et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2025

Association of IL-10, IL-6, and TNF-α polymorphisms with acute coronary syndrome risk: a systematic review, meta-analysis, and trial sequential analysis.

Luo Y et al.

Bmc Medical Genomics, 2025

Association of the IL-6R rs2228145 polymorphism with diabetic nephropathy: A case-control study.

Izakovicova P et al.

Journal of Diabetes Investigation, 2025

The Role of Cytokine Gene Polymorphisms in Rehabilitation Outcome After Traumatic Brain Injury.

Guerini FR et al.

Cells, 2025

40710309 (PubMed )
Supplement: cells-14-01056-s001.zip › cells-3695609-supplementary.xlsx › Foglio1

Are single nucleotide polymorphisms underutilized for guiding treatment of inflammatory bowel disease?

van der Werf J et al.

Immunology and Cell Biology, 2025

Significant Association of Interleukin-6 Polymorphism and Clinical Data with COVID-19 Severity in the Southwest of Iran.

Sheykhi-Sabzehpoush M et al.

Genetic Testing and Molecular Biomarkers, 2025

Association Between Genetic Variants in TNF, IL6, and IL1B Genes and Severity of COVID-19: A Cross-Sectional Study of Patients from Southern Brazil.

Feira MF et al.

Diagnostics (basel, Switzerland), 2025

40506975 (PubMed )
Supplement: diagnostics-15-01403-s001.zip › Supplementary_table_1_-_Genotypic_frequencies_and_analysis_of_dominant_and_recessive_models_for_variants_in_the_IL1B__IL6_and_TNF_Gene__n_______.__Hospitalization_.xlsx › Planilha1

Advances in cytokine gene polymorphisms in tuberculosis.

Fu H et al.

Msphere, 2025

The interleukin gene landscape: understanding its influence on inflammatory mechanisms in apical periodontitis.

Omran TZ et al.

Molecular Biology Reports, 2025

Protective Genes Against Alzheimer's Disease: Case Review and Therapeutic Implications.

Hossain N et al.

Dementia and Neurocognitive Disorders, 2025

Association of VDR and TMPRSS2 gene polymorphisms with COVID-19 severity: a computational and clinical study.

Verma S et al.

Molecular Biology Reports, 2025

Impact of IL-6 rs1800795 and rs1800796 polymorphisms on clinical outcomes of COVID-19: a study on severity of disease in Turkish population.

Cekin N et al.

Mammalian Genome : Official Journal of the International Mammalian Genome Society, 2025

Influence of Cytokine-Related genetic variants in TNF, IL6, IL1β, and IFNγ genes in the thalidomide treatment for Erythema nodosum leprosum in a Brazilian population sample.

Maciel-Fiuza MF et al.

Human Immunology, 2025

The influence of genetic variants of IL-6 (-174 G/C) and INFγ (+ 874 A/T) and their impact on anemic Sudanese children with kidney failure.

Makkawi AAMA et al.

Bmc Research Notes, 2025

Genetics of Long COVID: Exploring the Molecular Drivers of Persistent Pulmonary Vascular Disease Symptoms.

Ayyoub S et al.

Infectious Disease Reports, 2025

An integrated approach to predict genetic risk for Mosquito-Borne diseases in the local Population of Tehsil Haripur, Khyber Pakhtunkhwa, Pakistan.

Basri R et al.

Scientific Reports, 2025

39875533 (PubMed )
Supplement: 41598_2025_88095_MOESM1_ESM.docx

Association of IL6 Gene Polymorphisms and Neurological Disorders: Insights from Integrated Bioinformatics and Meta-Analysis.

Harun-Or-Roshid M et al.

Neuromolecular Medicine, 2025

An IL-6 promoter variant (-174 G/C) augments IL-6 production and alters skeletal muscle transcription in response to exercise in mice.

Watson LE et al.

Journal of Applied Physiology (bethesda, Md. : 1985), 2025

Single Nucleotide Polymorphisms and Tendon/Ligament Injuries in Athletes: A Systematic Review and Meta-analysis.

Fukuyama Y et al.

International Journal of Sports Medicine, 2025

Investigation of Interleukin-6 -572G/C Gene Polymorphism in Vitiligo Patients.

Yukcu F et al.

Journal of Clinical Practice and Research, 2025

Study of TNF-α, IFN-γ, IL-10, TGF-β and IL-6 Gene Polymorphisms in a Cohort of Professionals Who Worked in the First Pandemic Wave in the Brazilian Amazon.

Marcelino BDR et al.

Critical Reviews in Immunology, 2025

The effect of eight different gene polymorphisms on osteopenia and osteoporosis in the Turkish population.

Uzun N et al.

Revista Da Associacao Medica Brasileira (1992), 2025

Pharmacogenomics and genetic ancestry in Colombia: a study on all variant drug annotations of PharmGKB.

Acosta-Monterrosa AA et al.

Frontiers in Pharmacology, 2025

40949159 (PubMed )
Supplement: Table1.xlsx › Studies
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."