Associated Papers
CHIP ahoy: charting a decade of discovery in clonal hematopoiesis.
Wong CK et al.
Haematologica, 2026
Role of Interleukin-6 in Atherothrombosis and Myocardial Infarction.
Huse C et al.
Current Atherosclerosis Reports, 2026
Inflammageing and clonal haematopoiesis interplay and their impact on human disease.
Hajishengallis G et al.
Nature Reviews. Molecular Cell Biology, 2026
Impact of rare JAK/STAT germline mutations on vaccination-induced innate immune responses in a Tyrolian population.
Hennighausen L et al.
International Journal of Biological Sciences, 2026
Novel and emerging therapeutic strategies for clonal haematopoiesis.
Hosseini M et al.
Haematologica, 2025
Genetic Downregulation of Interleukin-6 Signaling and Arteriolosclerotic Cerebral Small Vessel Disease: A Drug Target Mendelian Randomization Analysis.
Tchuisseu-Kwangoua LA et al.
Journal of the American Heart Association, 2025
Dissecting regulatory non-coding GWAS loci reveals fibroblast causal genes with pathophysiological relevance to heart failure.
Gill R et al.
Nature Communications, 2025
Correlates and consequences of clonal hematopoiesis expansion rate: a 16-year longitudinal study of 6976 women.
Pershad Y et al.
Blood, 2025
A coding single nucleotide polymorphism in the interleukin-6 receptor enhances IL-6 signalling in CD4 T cells and predicts treatment response to tocilizumab in giant cell arteritis.
Zorc R et al.
Annals of the Rheumatic Diseases, 2025
Association of the IL-6R rs2228145 polymorphism with diabetic nephropathy: A case-control study.
Izakovicova P et al.
Journal of Diabetes Investigation, 2025
Proinflammatory transcriptomic and kinomic alterations in astrocytes derived from patients with familial Alzheimer's disease.
Siciliano B et al.
Brain, Behavior, & Immunity - Health, 2025
Does the Single Nucleotide Polymorphism rs2228145 in IL6R Truly Reflect IL-6 Signaling in Mendelian Randomization Studies?
Zhu M et al.
Immune Network, 2025
Genetic interleukin-6 receptor blockade, Chronic Disease Risk and Longevity. Results from the Women's Health Initiative.
Wissel S et al.
European Journal of Preventive Cardiology, 2025
Multi-omic insights from a multi-ancestry genome-wide meta-analysis of ankylosing spondylitis reveal novel pathways of disease susceptibility.
Brown M et al.
Research Square, 2025
The Role of Cytokine Gene Polymorphisms in Rehabilitation Outcome After Traumatic Brain Injury.
Guerini FR et al.
Cells, 2025
Clonal Hematopoiesis of Indeterminate Potential Is Associated With Incident Abdominal Aortic Aneurysm.
Tan Y et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2025
Associations of genetic polymorphisms with clinical response to tocilizumab in Chinese rheumatoid arthritis patients.
Qin W et al.
International Immunopharmacology, 2025
Genetic evidence for the causal effect of clonal hematopoiesis on pulmonary arterial hypertension.
Qiu JY et al.
Bmc Cardiovascular Disorders, 2025
Enhanced Interleukin 6 Trans-Signaling Modulates Disease Process in Amyotrophic Lateral Sclerosis Mouse Models.
Milligan C et al.
Brain Sciences, 2025
Correlates and Consequences of Clonal Hematopoiesis Expansion Rate: A 15-Year Longitudinal Study of 6,986 Women.
Pershad Y et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
Epidermal second-hit mutation in MVK gene associated with linear porokeratosis.
Zhao A et al.
Genes & Diseases, 2025
Pharmacogenomic landscape of TNF inhibitors in the Middle Eastern Qatari population.
Jan Z et al.
Frontiers in Immunology, 2025
Leveraging large-scale multi-omics evidences to identify therapeutic targets from genome-wide association studies.
Lessard S et al.
Bmc Genomics, 2024
Genome-wide studies define new genetic mechanisms of IgA vasculitis.
Liu L et al.
Medrxiv : the Preprint Server for Health Sciences, 2024
Chronic TNF in the aging microenvironment exacerbates Tet2 loss-of-function myeloid expansion.
Quin C et al.
Blood Advances, 2024
Pharmacokinetic and neuroimmune pharmacogenetic impacts on slow-release morphine cancer pain control and adverse effects.
Barratt DT et al.
The Pharmacogenomics Journal, 2024
Genetic Interleukin-6 Receptor Variant Is Not Associated With Rejection and Mortality After Heart Transplantation.
Amancherla K et al.
Journal of Cardiac Failure, 2024
No Association of Polymorphisms in the Genes Encoding Interleukin-6 and Interleukin-6 Receptor Subunit Alpha with the Risk of Keloids in Polish Patients.
Dmytrzak A et al.
International Journal of Molecular Sciences, 2024
Genetics of ischemic stroke functional outcome.
Carnwath TP et al.
Journal of Neurology, 2024
Heterogeneous associations between interleukin-6 receptor variants and phenotypes across ancestries and implications for therapy.
Wang X et al.
Scientific Reports, 2024
Polymorphic markers of several immune regulatory genes modulate the susceptibility for eczema and related phenotypes in children.
Kung CJS et al.
Translational Pediatrics, 2024
In the context of the triple burden of malnutrition: A systematic review of gene-diet interactions and nutritional status.
Tan PY et al.
Critical Reviews in Food Science and Nutrition, 2024
Impact of IL-6 and IL-6r variants on HIV-1 susceptibility and progression to AIDS: a case-control study in a Moroccan population.
Haddaji A et al.
Nucleosides, Nucleotides & Nucleic Acids, 2024
Association between clonal hematopoiesis-related gene mutations and unfavorable functional outcome in patients with large-artery atherosclerotic stroke.
Qiu X et al.
European Journal of Medical Research, 2023
Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.
Yu Z et al.
The Journal of Clinical Investigation, 2023
The Association of Selected GWAS Reported AD Risk Loci with CSF Biomarker Levels and Cognitive Decline in Slovenian Patients.
Vogrinc D et al.
International Journal of Molecular Sciences, 2023
Association of Single Nucleotide Polymorphisms of Cytokine Genes with Depression, Schizophrenia and Bipolar Disorder.
Mikhalitskaya EV et al.
Genes, 2023
Levels of Soluble Interleukin 6 Receptor and Asp358Ala Are Associated With Cognitive Performance and Alzheimer Disease Biomarkers.
Quillen D et al.
Neurology(r) Neuroimmunology & Neuroinflammation, 2023
Clonal Hematopoiesis and the Heart: a Toxic Relationship.
Jensen JL et al.
Current Oncology Reports, 2023
The effect of interleukin-6 signaling on severe malaria: A Mendelian randomization analysis.
Hamilton F et al.
International Journal of Infectious Diseases : Ijid : Official Publication of the International Society for Infectious Diseases, 2023
Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program.
Small AM et al.
Circulation, 2023
Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends CM et al.
Blood, 2023
Altered IL-6 signalling and risk of tuberculosis disease: a meta-analysis and Mendelian randomisation study.
Hamilton F et al.
Medrxiv : the Preprint Server for Health Sciences, 2023
Genetic Determinants of IL-6 Levels and Risk of ESKD.
Wheless L et al.
Kidney360, 2023
Interleukin-6 Receptor Polymorphism Attenuates Clonal Hematopoiesis-Mediated Coronary Artery Disease Risk Among 451 180 Individuals in the UK Biobank.
Vlasschaert C et al.
Circulation, 2023
Clonal hematopoiesis, somatic mosaicism, and age-associated disease.
Evans MA et al.
Physiological Reviews, 2023
Genomic Aging, Clonal Hematopoiesis, and Cardiovascular Disease.
Natarajan P
Arteriosclerosis, Thrombosis, and Vascular Biology, 2023