Varaico: Literature-Extracted Genetic Variants

Gene:IL6ST
Variant:p.G148R
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IL6ST

NM_002184.4:p.G148R

Associated Papers

Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry.

Bateman NW et al.

Iscience, 2022

35036865 (PubMed )
Supplement: mmc2.xlsx › SupplementalTable1A

A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC).

Low JL et al.

Ebiomedicine, 2021

33529999 (PubMed )
Supplement: mmc2.xlsx › Table_S2

Genomic Multiple Sclerosis Risk Variants Modulate the Expression of the ANKRD55-IL6ST Gene Region in Immature Dendritic Cells.

Mena J et al.

Frontiers in Immunology, 2021

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study.

Bonomi A et al.

Genes and Immunity, 2020

Prognostic role of genetic polymorphisms of the interleukin-6 signaling pathway in patients with severe heart failure.

Hansen PR et al.

The Pharmacogenomics Journal, 2019

Association of Variants in IL6-Related Genes with Lung Cancer Risk in Moroccan Population.

Kaanane H et al.

Lung, 2019

Tumorigenicity-associated characteristics of human iPS cell lines.

Yasuda S et al.

Plos One, 2018

30286143 (PubMed )
Supplement: pone.0205022.s007.xlsx › Sheet1

Genes implicated in thiopurine-induced toxicity: Comparing TPMT enzyme activity with clinical phenotype and exome data in a paediatric IBD cohort.

Coelho T et al.

Scientific Reports, 2016

Identification of HPV integration and gene mutation in HeLa cell line by integrated analysis of RNA-Seq and MS/MS data.

Sun H et al.

Journal of Proteome Research, 2015

25698088 (PubMed )
Supplement: pr500944c_si_009.xlsx › SNV

No evidence of association between functional polymorphisms located within IL6R and IL6ST genes and Henoch-Schönlein purpura.

López-Mejías R et al.

Tissue Antigens, 2013

Inherited variants in regulatory T cell genes and outcome of ovarian cancer.

Goode EL et al.

Plos One, 2013

23382860 (PubMed )
Supplement: pone.0053903.s002.xlsx › Supplemental_Table_2

No evidence of association between functional polymorphisms located within IL6R and IL6ST genes and systemic sclerosis.

Cénit MC et al.

Tissue Antigens, 2012

Performance of an adipokine pathway-based multilocus genetic risk score for prostate cancer risk prediction.

Ribeiro RJ et al.

Plos One, 2012

Body iron stores and glucose intolerance in premenopausal women: role of hyperandrogenism, insulin resistance, and genomic variants related to inflammation, oxidative stress, and iron metabolism.

Martínez-García MA et al.

Diabetes Care, 2009

A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population.

Benrick A et al.

Regulatory Peptides, 2008

Genomic variants in polycystic ovary syndrome.

Luque-Ramírez M et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2006

Genetic basis of metabolic abnormalities in polycystic ovary syndrome: implications for therapy.

Roldán B et al.

American Journal of Pharmacogenomics : Genomics-related Research in Drug Development and Clinical Practice, 2004

Association of polymorphisms in the interleukin 6 receptor complex with obesity and hyperandrogenism.

Escobar-Morreale HF et al.

Obesity Research, 2003

Genetics of polycystic ovary syndrome: searching for the way out of the labyrinth.

Diamanti-Kandarakis E et al.

Human Reproduction Update, 0

Polycystic ovary syndrome: the influence of environmental and genetic factors.

Diamanti-Kandarakis E et al.

Hormones (athens, Greece), 0

Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response.

Simoni M et al.

Human Reproduction Update, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."