Associated Papers
Genome-wide association analyses of autoimmune hypothyroidism reveal autoimmune and thyroid-specific contributions and an inverse relationship with cancer risk.
Reeve MP et al.
Nature Genetics, 2026
rs6897932 (C>T) and rs987106 (A>T) variants in the IL7RA gene are correlated with the susceptibility and the clinical features of systemic lupus erythematosus.
Sarpeleh F et al.
Lupus, 2026
Sustained HIV-1 remission after heterozygous CCR5Δ32 stem cell transplantation.
Gaebler C et al.
Nature, 2026
Germline Variants in the Immune Response-Related Genes: Possible Modifying Effect on Age-Dependent BRCA1 Penetrance in Breast Cancer Patient.
Kuligina ES et al.
Cancers, 2025
Activity of Brigatinib in Patients With Crizotinib-Resistant ALK-positive Non-Small-Cell Lung Cancer According to ALK Fusion and Mutation Status.
Bazhenova L et al.
Clinical Lung Cancer, 2025
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.
Dand N et al.
Nature Communications, 2025
Single-cell DNA and surface protein characterization of high hyperdiploid acute lymphoblastic leukemia at diagnosis and during treatment.
Aertgeerts M et al.
Hemasphere, 2025
Translational and clinical comparison of whole genome and transcriptome to panel sequencing in precision oncology.
Kerle IA et al.
Npj Precision Oncology, 2025
The Polygenic Nature of Multiple Sclerosis: Genetic Variants, Immunological Modulation, and Environmental Connections.
Khan Z et al.
Endocrine, Metabolic & Immune Disorders Drug Targets, 2025
IL-7-dependent and -independent lineages of IL-7R-dependent human T cells.
Arango-Franco CA et al.
The Journal of Clinical Investigation, 2024
Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.
Vanni I et al.
Journal of Translational Medicine, 2024
Novel Synonymous Variant in IL7R Causes Preferential Expression of the Soluble Isoform.
Mackeh R et al.
Journal of Clinical Immunology, 2024
Prognostic impact of IL7R mutations on acute myeloid leukemia.
Tao Q et al.
Therapeutic Advances in Hematology, 2024
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.
Dand N et al.
Medrxiv : the Preprint Server for Health Sciences, 2023
RaScALL: Rapid (Ra) screening (Sc) of RNA-seq data for prognostically significant genomic alterations in acute lymphoblastic leukaemia (ALL).
Rehn J et al.
Plos Genetics, 2022
Cytokine pathway variants modulate platelet production: IFNA16 is a thrombocytosis susceptibility locus in humans.
Gnatenko DV et al.
Blood Advances, 2022
Monitoring of Leukemia Clones in B-cell Acute Lymphoblastic Leukemia at Diagnosis and During Treatment by Single-cell DNA Amplicon Sequencing.
Meyers S et al.
Hemasphere, 2022
Genetic risk variants for multiple sclerosis are linked to differences in alternative pre-mRNA splicing.
Putscher E et al.
Frontiers in Immunology, 2022
U2AF2 binds IL7R exon 6 ectopically and represses its inclusion.
Schott G et al.
Rna (new York, N.y.), 2021
Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity.
Yoshizawa T et al.
Npj Precision Oncology, 2021
A bioinformatic approach to investigating cytokine genes and their receptor variants in relation to COVID-19 progression.
Karakas Celik S et al.
International Journal of Immunogenetics, 2021
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC).
Low JL et al.
Ebiomedicine, 2021
Identification of New Tumor-Related Gene Mutations in Chinese Gastrointestinal Stromal Tumors.
Feng Y et al.
Frontiers in Cell and Developmental Biology, 2021
Assessment of IL-7RA T244I Polymorphism as a Risk Factor of Multiple Sclerosis in Turkish Population.
Ünsal MA et al.
Noro Psikiyatri Arsivi, 2020
Analysis of 47 Non-MHC Ankylosing Spondylitis Susceptibility Loci Regarding Associated Variants across Whites and Han Chinese.
Zheng X et al.
The Journal of Rheumatology, 2020
Interleukin 7 receptor T244I polymorphism and the multiple sclerosis susceptibility: a meta-analysis.
Sahami-Fard MH et al.
Journal of Neuroimmunology, 2020
IL7RA genetic variants differentially affect IL-7Rα expression and alternative splicing: a role in autoimmune and infectious diseases?
Lundtoft C et al.
Genes and Immunity, 2020
An IL7RA exon 5 polymorphism is associated with impaired IL-7Rα splicing and protection against tuberculosis in Ghana.
Lundtoft C et al.
Genes and Immunity, 2019
Association Between IL7R Promoter Polymorphisms and Multiple Sclerosis in Turkish Population.
Simsek H et al.
Journal of Molecular Neuroscience : Mn, 2019
Axitinib overcomes multiple imatinib resistant cKIT mutations including the gatekeeper mutation T670I in gastrointestinal stromal tumors.
Liu F et al.
Therapeutic Advances in Medical Oncology, 2019
Whole-exome sequencing insights into pulmonary artery sarcoma mimicking pulmonary embolism: a case report and review.
Wu Y et al.
Oncotargets and Therapy, 2019
Deep Resequencing of Ulcerative Colitis-Associated Genes Identifies Novel Variants in Candidate Genes in the Korean Population.
Moon CM et al.
Inflammatory Bowel Diseases, 2018
Multiple sclerosis genetics: Results from meta-analyses of candidate-gene association studies.
Tizaoui K
Cytokine, 2018