Associated Papers
The ILK-PINCH-parvin complex: a conserved primary adhesome regulating biological processes.
Ain U et al.
Histochemistry and Cell Biology, 2025
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer.
Ji C et al.
Cell Death & Disease, 2022
Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion.
Vaynberg J et al.
Nature Communications, 2018
Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout mice.
Dai J et al.
Circulation. Heart Failure, 2014
Integrin-linked kinase: not so 'pseudo' after all.
Hannigan GE et al.
Oncogene, 2011
Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase.
Fukuda K et al.
The Journal of Biological Chemistry, 2011
Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation.
Maydan M et al.
Plos One, 2010
Integrin-linked kinase is an adaptor with essential functions during mouse development.
Lange A et al.
Nature, 2009
Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex.
Postel R et al.
Developmental Biology, 2008
Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells.
Knöll R et al.
Circulation, 2007
The gamma-parvin-integrin-linked kinase complex is critically involved in leukocyte-substrate interaction.
Yoshimi R et al.
Journal of Immunology (baltimore, Md. : 1950), 2006
Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction.
Yamaji S et al.
The Journal of Cell Biology, 2004
A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction.
Yamaji S et al.
The Journal of Cell Biology, 2001
Disruption of the integrin-linked kinase (ILK) pseudokinase domain affects kidney development in mice.
Bulus N et al.
The Journal of Biological Chemistry, 0
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