Varaico: Literature-Extracted Genetic Variants

Gene:IMPDH2
Variant:p.L263F
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IMPDH2

NM_000884.3:p.L263F

Associated Papers

Role of Genetic Variations in the Hepatic Handling of Drugs.

Marin JJG et al.

International Journal of Molecular Sciences, 2020

Pharmacogenetics Biomarkers Predictive of Drug Pharmacodynamics as an Additional Tool to Therapeutic Drug Monitoring.

Haufroid V et al.

Therapeutic Drug Monitoring, 2019

Inosine Monophosphate Dehydrogenase Pharmacogenetics in Hematopoietic Cell Transplantation Patients.

McCune JS et al.

Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation, 2018

Genetic variations in the mycophenolate mofetil target enzyme are associated with acute GVHD risk after related and unrelated hematopoietic cell transplantation.

Cao W et al.

Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation, 2012

The influence of pharmacogenetics and cofactors on clinical outcomes in kidney transplantation.

Picard N et al.

Expert Opinion on Drug Metabolism & Toxicology, 2011

Polymorphisms in type I and II inosine monophosphate dehydrogenase genes and association with clinical outcome in patients on mycophenolate mofetil.

Gensburger O et al.

Pharmacogenetics and Genomics, 2010

An inosine 5'-monophosphate dehydrogenase 2 single-nucleotide polymorphism impairs the effect of mycophenolic acid.

Winnicki W et al.

The Pharmacogenomics Journal, 2010

Functional polymorphisms and methotrexate treatment outcome in recent-onset rheumatoid arthritis.

Kooloos WM et al.

Pharmacogenomics, 2010

IMPDH2 genetic polymorphism: a promoter single-nucleotide polymorphism disrupts a cyclic adenosine monophosphate responsive element.

Garat A et al.

Genetic Testing and Molecular Biomarkers, 2009

IMPDH1 gene polymorphisms and association with acute rejection in renal transplant patients.

Wang J et al.

Clinical Pharmacology and Therapeutics, 2008

A novel variant L263F in human inosine 5'-monophosphate dehydrogenase 2 is associated with diminished enzyme activity.

Wang J et al.

Pharmacogenetics and Genomics, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."