Associated Papers
Rationally-Stabilized Inhibited State of IMPDH Proposes a Novel Targeting Approach Involving Its Cross-Domain and Assembly Suppression.
Sattari S et al.
Molecular Biotechnology, 2025
Light-sensitive phosphorylation regulates enzyme activity and filament assembly of human IMPDH1 retinal splice variants.
Calise SJ et al.
Biorxiv : the Preprint Server for Biology, 2023
Point mutations in IMPDH2 which cause early-onset neurodevelopmental disorders disrupt enzyme regulation and filament structure.
O'Neill AG et al.
Biorxiv : the Preprint Server for Biology, 2023
IMPDH dysregulation in disease: a mini review.
Burrell AL et al.
Biochemical Society Transactions, 2022
IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Burrell AL et al.
Nature Structural & Molecular Biology, 2022
Mutation frequency of IMPDH1 gene of Han population in Ganzhou City.
Shumei L et al.
Advances in Experimental Medicine and Biology, 2010
Investigating the mechanism of disease in the RP10 form of retinitis pigmentosa.
Spellicy CJ et al.
Advances in Experimental Medicine and Biology, 2010
IMP dehydrogenase-linked retinitis pigmentosa.
Hedstrom L
Nucleosides, Nucleotides & Nucleic Acids, 2008
Spectrum and frequency of mutations in IMPDH1 associated with autosomal dominant retinitis pigmentosa and leber congenital amaurosis.
Bowne SJ et al.
Investigative Ophthalmology & Visual Science, 2006
Phenotypic characterization of a large family with RP10 autosomal-dominant retinitis pigmentosa: an Asp226Asn mutation in the IMPDH1 gene.
Kozma P et al.
American Journal of Ophthalmology, 2005
Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid binding.
Mortimer SE et al.
The Biochemical Journal, 2005
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
Aherne A et al.
Human Molecular Genetics, 2004
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