Associated Papers
The power of five - inositol polyphosphate 5-phosphatase gene mutations at the intersection of development and disease.
McGrath MJ et al.
Febs Letters, 2025
JAK2-V617F is a negative regulation factor of SHIP1 protein and thus influences the AKT signaling pathway in patients with Myeloproliferative neoplasm (MPN).
Glück M et al.
The International Journal of Biochemistry & Cell Biology, 2022
Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins.
Ehm PAH et al.
Cellular Signalling, 2019
JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis.
Tuncay H et al.
Nature Communications, 2015
Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling.
Brauer H et al.
Cellular Signalling, 2012
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