Associated Papers
Increasing Ciliary ARL13B Expression Drives Active and Inhibitor-Resistant Smoothened and GLI into Glioma Primary Cilia.
Shi P et al.
Cells, 2023
Multiple ciliary localization signals control INPP5E ciliary targeting.
Cilleros-Rodriguez D et al.
Elife, 2022
Reversal of ciliary mechanisms of disassembly rescues olfactory dysfunction in ciliopathies.
Xie C et al.
Jci Insight, 2022
The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling.
Schembs L et al.
Cell Reports, 2022
Plasma membrane phosphatidylinositol (4,5)-bisphosphate is critical for determination of epithelial characteristics.
Kanemaru K et al.
Nature Communications, 2022
INPP5E controls ciliary localization of phospholipids and the odor response in olfactory sensory neurons.
Ukhanov K et al.
Journal of Cell Science, 2022
A high-avidity biosensor reveals plasma membrane PI(3,4)P2 is predominantly a class I PI3K signaling product.
Goulden BD et al.
The Journal of Cell Biology, 2019
30591513 (PubMed )
Supplement: JCB_201809026_sm.pdf
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision.
Phua SC et al.
Cell, 2017
Autophagosome-lysosome fusion in neurons requires INPP5E, a protein associated with Joubert syndrome.
Hasegawa J et al.
The Embo Journal, 2016
Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling.
Garcia-Gonzalo FR et al.
Developmental Cell, 2015
Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output.
Chávez M et al.
Developmental Cell, 2015
Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies.
Bielas SL et al.
Nature Genetics, 2009
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