Varaico: Literature-Extracted Genetic Variants

Gene:INPPL1
Variant:p.D607A
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INPPL1

NM_001567.4:p.D607A

Associated Papers

Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition.

Wei W et al.

The Journal of Experimental Medicine, 2023

Structural basis for interdomain communication in SHIP2 providing high phosphatase activity.

Le Coq J et al.

Elife, 2017

ARAP3 binding to phosphatidylinositol-(3,4,5)-trisphosphate depends on N-terminal tandem PH domains and adjacent sequences.

Craig HE et al.

Cellular Signalling, 2010

SHIP2 (SH2 domain-containing inositol phosphatase 2) SH2 domain negatively controls SHIP2 monoubiquitination in response to epidermal growth factor.

De Schutter J et al.

The Journal of Biological Chemistry, 2009

SHIP2 interaction with the cytoskeletal protein Vinexin.

Paternotte N et al.

The Febs Journal, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."