Varaico: Literature-Extracted Genetic Variants

Gene:INS
Variant:p.L10L
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INS

NM_000207.3:p.L10L

Associated Papers

Genetic polymorphism of glucokinase on the risk of type 2 diabetes and impaired glucose regulation: evidence based on 298,468 subjects.

Fu D et al.

Plos One, 2013

Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose.

Li X et al.

Diabetes, 2009

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.

Sparsø T et al.

Diabetologia, 2008

A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses.

Weedon MN et al.

American Journal of Human Genetics, 2006

A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites.

Rose CS et al.

Diabetes, 2005

Glucokinase (GCK) mutations in hyper- and hypoglycemia: maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy.

Gloyn AL

Human Mutation, 2003

Glucose transporter 4 gene: association studies pertaining to alleles of two polymorphisms in extremely obese children and adolescents and in normal and underweight controls.

Friedel S et al.

Annals of the New York Academy of Sciences, 2002

Human alpha-galactosidase A: high plasma activity expressed by the -30G-->A allele.

Fitzmaurice TF et al.

Journal of Inherited Metabolic Disease, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."