Varaico: Literature-Extracted Genetic Variants

Gene:INSR
Variant:p.S503A
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INSR

NM_000208.4:p.S503A

Associated Papers

Defective insulin clearance plays a primary role in the pathogenesis of chronic kidney disease in mice with null deletion of Ceacam2 gene.

Kumarasamy S et al.

Biorxiv : the Preprint Server for Biology, 2025

Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice.

Russo L et al.

Diabetologia, 2017

Susceptibility to diet-induced hepatic steatosis and glucocorticoid resistance in FK506-binding protein 52-deficient mice.

Warrier M et al.

Endocrinology, 2010

Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism.

DeAngelis AM et al.

Diabetes, 2008

Comparison of the intracellular trafficking of two alternatively spliced isoforms of pp120, a substrate of the insulin receptor tyrosine kinase.

Choice CV et al.

Journal of Cellular Biochemistry, 1999

Receptor-mediated internalization of insulin. Potential role of pp120/HA4, a substrate of the insulin receptor kinase.

Formisano P et al.

The Journal of Biological Chemistry, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."