Associated Papers
Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9.
Eaton JD et al.
Elife, 2024
Structural basis of Integrator-dependent RNA polymerase II termination.
Fianu I et al.
Nature, 2024
Structural basis of INTAC-regulated transcription.
Zheng H et al.
Protein & Cell, 2023
R-loop-dependent promoter-proximal termination ensures genome stability.
Xu C et al.
Nature, 2023
Structural basis of Integrator-mediated transcription regulation.
Fianu I et al.
Science (new York, N.y.), 2021
Integrator enforces the fidelity of transcriptional termination at protein-coding genes.
Dasilva LF et al.
Science Advances, 2021
Structure of the catalytic core of the Integrator complex.
Pfleiderer MM et al.
Molecular Cell, 2021
Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
Baillat D et al.
Cell, 2005
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