Associated Papers
Genome-wide association analyses of autoimmune hypothyroidism reveal autoimmune and thyroid-specific contributions and an inverse relationship with cancer risk.
Reeve MP et al.
Nature Genetics, 2026
Discriminating activating, deactivating and resistance variants in protein kinases.
Singh G et al.
Genome Medicine, 2025
Genetic polymorphisms in external apical root resorption and orthodontic tooth movements: A systematic review.
Andrade ALCÁ et al.
Korean Journal of Orthodontics, 2024
Comprehensive Assessment of Indian Variations in the Druggable Kinome Landscape Highlights Distinct Insights at the Sequence, Structure and Pharmacogenomic Stratum.
Panda G et al.
Frontiers in Pharmacology, 2022
Synergistic effect of genetic polymorphisms in TLR6 and TLR10 genes on the risk of pulmonary tuberculosis in a Moldavian population.
Varzari A et al.
Innate Immunity, 2021
Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach.
Akhtar M et al.
Biology, 2021
Multidimensional Mutational Profiling of the Indian HNSCC Sub-Population Provides IRAK1, a Novel Driver Gene and Potential Druggable Target.
Desai SS et al.
Frontiers in Oncology, 2021
Distinct Molecular Landscape of Epstein-Barr Virus Associated Pulmonary Lymphoepithelioma-Like Carcinoma Revealed by Genomic Sequencing.
Chau SL et al.
Cancers, 2020
Common variants of genes encoding TLR4 and TLR4 pathway members TIRAP and IRAK1 are effective on MCP1, IL6, IL1β, and TNFα levels in type 2 diabetes and insulin resistance.
Degirmenci I et al.
Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.], 2019
IRAK1 variant is protective for orthodontic-induced external apical root resorption.
Pereira S et al.
Oral Diseases, 2016
Variants in IRAK1-MECP2 region confer susceptibility to autoimmune thyroid diseases.
Song RH et al.
Molecular and Cellular Endocrinology, 2015
Association of an activity-enhancing variant of IRAK1 and an MECP2-IRAK1 haplotype with increased susceptibility to rheumatoid arthritis.
Han TU et al.
Arthritis and Rheumatism, 2013
Genetic variation in the TNF receptor-associated factor 6 gene is associated with susceptibility to sepsis-induced acute lung injury.
Song Z et al.
Journal of Translational Medicine, 2012
SNP-based large-scale identification of allele-specific gene expression in human B cells.
Song MY et al.
Gene, 2012
IRAK1 functional genetic variant affects severity of septic shock.
Toubiana J et al.
Critical Care Medicine, 2010
A polymorphism in the 3'-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of miR-146a, is associated with rheumatoid arthritis susceptibility.
Chatzikyriakidou A et al.
Joint Bone Spine, 2010
Association of genetic variants with chronic kidney disease in Japanese individuals with type 2 diabetes mellitus.
Yoshida T et al.
International Journal of Molecular Medicine, 2009
Genetic factors for ischemic and hemorrhagic stroke in Japanese individuals.
Yamada Y et al.
Stroke, 2008
The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study.
Lakoski SG et al.
Experimental and Molecular Pathology, 2007
Association of a haplotype (196Phe/532Ser) in the interleukin-1-receptor-associated kinase (IRAK1) gene with low radial bone mineral density in two independent populations.
Ishida R et al.
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 2003