Associated Papers
Genome-wide association analyses of autoimmune hypothyroidism reveal autoimmune and thyroid-specific contributions and an inverse relationship with cancer risk.
Reeve MP et al.
Nature Genetics, 2026
Xq28 Variants as Novel Male-Specific Susceptibility Factors for Hirschsprung Disease.
Xie X et al.
The Journal of Surgical Research, 2026
Discriminating activating, deactivating and resistance variants in protein kinases.
Singh G et al.
Genome Medicine, 2025
Type I interferon associated epistasis may contribute to early disease-onset and high disease activity in juvenile-onset lupus.
Renaudineau Y et al.
Clinical Immunology (orlando, Fla.), 2024
A Comprehensive Clinicopathologic and Molecular Study of 19 Primary Effusion Lymphomas in HIV-infected Patients.
Calvani J et al.
The American Journal of Surgical Pathology, 2022
Comprehensive Assessment of Indian Variations in the Druggable Kinome Landscape Highlights Distinct Insights at the Sequence, Structure and Pharmacogenomic Stratum.
Panda G et al.
Frontiers in Pharmacology, 2022
Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach.
Akhtar M et al.
Biology, 2021
Multidimensional Mutational Profiling of the Indian HNSCC Sub-Population Provides IRAK1, a Novel Driver Gene and Potential Druggable Target.
Desai SS et al.
Frontiers in Oncology, 2021
Host genetic variants in sepsis risk: a field synopsis and meta-analysis.
Lu H et al.
Critical Care (london, England), 2019
Targeting Myddosome Signaling in Waldenström's Macroglobulinemia with the Interleukin-1 Receptor-Associated Kinase 1/4 Inhibitor R191.
Ni H et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2018
Next-Generation Sequencing in the Understanding of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Biology.
Strahan R et al.
Viruses, 2016
Immunogenetics of rheumatoid arthritis: Understanding functional implications.
Messemaker TC et al.
Journal of Autoimmunity, 2015
Replication of GWAS Coding SNPs Implicates MMEL1 as a Potential Susceptibility Locus among Saudi Arabian Celiac Disease Patients.
Saadah OI et al.
Disease Markers, 2015
Interleukin 1 receptor-associated kinase 1 (IRAK1) mutation is a common, essential driver for Kaposi sarcoma herpesvirus lymphoma.
Yang D et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014
TBX1 mutation identified by exome sequencing in a Japanese family with 22q11.2 deletion syndrome-like craniofacial features and hypocalcemia.
Ogata T et al.
Plos One, 2014
New insight on the Xq28 association with systemic sclerosis.
Carmona FD et al.
Annals of the Rheumatic Diseases, 2013
Association of an activity-enhancing variant of IRAK1 and an MECP2-IRAK1 haplotype with increased susceptibility to rheumatoid arthritis.
Han TU et al.
Arthritis and Rheumatism, 2013
Toll-like receptor signaling pathway variants and prostate cancer mortality.
Stark JR et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2009
The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study.
Lakoski SG et al.
Experimental and Molecular Pathology, 2007
Lack of association between genetic variation in 9 innate immunity genes and baseline CRP levels.
Kozlowski P et al.
Annals of Human Genetics, 2006
Lack of Association Between Genetic Variation in 9 Innate Immunity Genes and Baseline CRP Levels.
Kozlowski P et al.
Annals of Human Genetics, 2006
Interactions of sequence variants in interleukin-1 receptor-associated kinase4 and the toll-like receptor 6-1-10 gene cluster increase prostate cancer risk.
Sun J et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2006
Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections.
Medvedev AE et al.
The Journal of Experimental Medicine, 2003
Association of a haplotype (196Phe/532Ser) in the interleukin-1-receptor-associated kinase (IRAK1) gene with low radial bone mineral density in two independent populations.
Ishida R et al.
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 2003