Varaico: Literature-Extracted Genetic Variants

Gene:IRAK1
Variant:p.K134R
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IRAK1

NM_001569.4:p.K134R

Associated Papers

An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy.

Liu PH et al.

Nature Cell Biology, 2019

Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activation.

Xiao H et al.

The Journal of Biological Chemistry, 2008

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation.

Conze DB et al.

Molecular and Cellular Biology, 2008

Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFkappaB activation pathways bifurcate at IL-1 receptor-associated kinase modification.

Yao J et al.

The Journal of Biological Chemistry, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."