Associated Papers
A frequent hypofunctional IRAK2 variant is associated with reduced spontaneous hepatitis C virus clearance.
Wang H et al.
Hepatology (baltimore, Md.), 2015
A coding IRAK2 protein variant compromises Toll-like receptor (TLR) signaling and is associated with colorectal cancer survival.
Wang H et al.
The Journal of Biological Chemistry, 2014
Human interleukin-1 receptor-associated kinase-2 is essential for Toll-like receptor-mediated transcriptional and post-transcriptional regulation of tumor necrosis factor alpha.
Flannery SM et al.
The Journal of Biological Chemistry, 2011
IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination.
Keating SE et al.
The Journal of Biological Chemistry, 2007
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