Varaico: Literature-Extracted Genetic Variants

Gene:IRAK4
Variant:p.Q143L
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IRAK4

NM_016123.4:p.Q143L

Associated Papers

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

Fragoza R et al.

Nature Communications, 2019

31515488 (PubMed )
Supplement: 41467_2019_11959_MOESM11_ESM.xlsx › SD7_-_Drug_Targets

Functional Polymorphisms in IRAKs Are Related to Hepatocellular Carcinoma Risk in Chinese Population.

Wang H et al.

Biomed Research International, 2018

Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome.

Rajeevan MS et al.

Human Immunology, 2015

Activating somatic mutations in diffuse large B-cell lymphomas: lessons from next generation sequencing and key elements in the precision medicine era.

Bohers E et al.

Leukemia & Lymphoma, 2015

IRAK4 and TLR3 Sequence Variants may Alter Breast Cancer Risk among African-American Women.

Yeyeodu ST et al.

Frontiers in Immunology, 2013

A nonsynonymous polymorphism of IRAK4 associated with increased prevalence of gram-positive infection and decreased response to toll-like receptor ligands.

Sutherland AM et al.

Journal of Innate Immunity, 2011

Lack of association between genetic variation in 9 innate immunity genes and baseline CRP levels.

Kozlowski P et al.

Annals of Human Genetics, 2006

Lack of Association Between Genetic Variation in 9 Innate Immunity Genes and Baseline CRP Levels.

Kozlowski P et al.

Annals of Human Genetics, 2006

Interactions of sequence variants in interleukin-1 receptor-associated kinase4 and the toll-like receptor 6-1-10 gene cluster increase prostate cancer risk.

Sun J et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."