Associated Papers
Perturbations of the ZED1 pseudokinase activate plant immunity.
Bastedo DP et al.
Plos Pathogens, 2019
Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
Wang L et al.
The Journal of Biological Chemistry, 2019
Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.
Pellegrini E et al.
Plos One, 2017
Rare mendelian primary immunodeficiency diseases associated with impaired NF-κB signaling.
Paciolla M et al.
Genes and Immunity, 2015
IRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assembly.
Ferrao R et al.
Molecular Cell, 2014
Immune diseases caused by mutations in kinases and components of the ubiquitin system.
Cohen P
Nature Immunology, 2014
Mutations in the NF-kappaB signaling pathway: implications for human disease.
Courtois G et al.
Oncogene, 2006
Inherited disorders of human Toll-like receptor signaling: immunological implications.
Ku CL et al.
Immunological Reviews, 2005
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