Varaico: Literature-Extracted Genetic Variants

Gene:IRAK4
Variant:p.A428T
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IRAK4

NM_016123.4:p.A428T

Associated Papers

A scalable approach to resolving variants of uncertain significance.

Tejura M et al.

Biorxiv : the Preprint Server for Biology, 2026

41727046 (PubMed )
Supplement: media-7.xlsx › VarChAMP_data_supp_mat_PP

IL-1 receptor-associated kinase family proteins: An overview of their role in liver disease.

Wang ZY et al.

European Journal of Pharmacology, 2024

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

Fragoza R et al.

Nature Communications, 2019

31515488 (PubMed )
Supplement: 41467_2019_11959_MOESM11_ESM.xlsx › SD7_-_Drug_Targets

Functional Polymorphisms in IRAKs Are Related to Hepatocellular Carcinoma Risk in Chinese Population.

Wang H et al.

Biomed Research International, 2018

Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome.

Rajeevan MS et al.

Human Immunology, 2015

Genetics of toll like receptor 9 in ANCA associated vasculitides.

Husmann CA et al.

Annals of the Rheumatic Diseases, 2014

IRAK4 and TLR3 Sequence Variants may Alter Breast Cancer Risk among African-American Women.

Yeyeodu ST et al.

Frontiers in Immunology, 2013

A nonsynonymous polymorphism of IRAK4 associated with increased prevalence of gram-positive infection and decreased response to toll-like receptor ligands.

Sutherland AM et al.

Journal of Innate Immunity, 2011

Lack of association between genetic variation in 9 innate immunity genes and baseline CRP levels.

Kozlowski P et al.

Annals of Human Genetics, 2006

Lack of Association Between Genetic Variation in 9 Innate Immunity Genes and Baseline CRP Levels.

Kozlowski P et al.

Annals of Human Genetics, 2006

Interactions of sequence variants in interleukin-1 receptor-associated kinase4 and the toll-like receptor 6-1-10 gene cluster increase prostate cancer risk.

Sun J et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."