Varaico: Literature-Extracted Genetic Variants

Gene:IRF1
Variant:p.E222K
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IRF1

NM_002198.3:p.E222K

Associated Papers

Base editing screens map mutations affecting interferon-γ signaling in cancer.

Coelho MA et al.

Cancer Cell, 2023

36669486 (PubMed )
Supplement: mmc4.xlsx › BE_variants_-clinical_relevance

Molecular dynamics simulations reveal the effect of mutations in the RING domains of BRCA1-BARD1 complex and its relevance to the prognosis of breast cancer.

Kiewhuo K et al.

Journal of Biomolecular Structure & Dynamics, 2023

Effect of novel leukemia mutations (K75E & E222K) on interferon regulatory factor 1 and its interaction with DNA: insights from molecular dynamics simulations and docking studies.

Kamaraj B et al.

Journal of Biomolecular Structure & Dynamics, 2021

Novel IRF-1 Mutations in a Small Cohort of Leukaemia Patients From Saudi Arabia

Alsamman K et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."