Associated Papers
Cysteine allostery and autoinhibition govern human STING oligomer functionality.
Chan R et al.
Nature Chemical Biology, 2025
IRF3-p300 axis controls global acetylation and mitotic progression.
Kim WJ et al.
Biochemical and Biophysical Research Communications, 2025
Characterization of distinct molecular interactions responsible for IRF3 and IRF7 phosphorylation and subsequent dimerization.
Dalskov L et al.
Nucleic Acids Research, 2020
The Structural Basis of IRF-3 Activation upon Phosphorylation.
Jing T et al.
Journal of Immunology (baltimore, Md. : 1950), 2020
The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death.
Zierhut C et al.
Cell, 2019
Ser386 phosphorylation of transcription factor IRF-3 induces dimerization and association with CBP/p300 without overall conformational change.
Takahasi K et al.
Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2010
Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association.
Clément JF et al.
Journal of Virology, 2008
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