Varaico: Literature-Extracted Genetic Variants

Gene:IRF3
Variant:p.S339A
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IRF3

NM_001571.6:p.S339A

Associated Papers

The Structural Basis of IRF-3 Activation upon Phosphorylation.

Jing T et al.

Journal of Immunology (baltimore, Md. : 1950), 2020

The tumor suppressor PTEN has a critical role in antiviral innate immunity.

Li S et al.

Nature Immunology, 2016

Epstein-Barr virus BGLF4 kinase suppresses the interferon regulatory factor 3 signaling pathway.

Wang JT et al.

Journal of Virology, 2009

Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association.

Clément JF et al.

Journal of Virology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."