Associated Papers
A novel noncanonical function for IRF6 in the recycling of E-cadherin.
Antiguas A et al.
Molecular Biology of the Cell, 2024
Causal Variations at IRF6 Gene Identified in Van der Woude Syndrome Pedigrees.
Yang CW et al.
The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-craniofacial Association, 2024
Germline mutations and developmental mosaicism underlying EGFR-mutant lung cancer.
Burr R et al.
Medrxiv : the Preprint Server for Health Sciences, 2023
A Comprehensive Genetic Analysis of Slovenian Families with Multiple Cases of Orofacial Clefts Reveals Novel Variants in the Genes IRF6, GRHL3, and TBX22.
Slavec L et al.
International Journal of Molecular Sciences, 2023
Non-random distribution of deleterious mutations in the DNA and protein-binding domains of IRF6 are associated with Van Der Woude syndrome.
Alade AA et al.
Molecular Genetics & Genomic Medicine, 2020
Interferon regulatory factor 6 is required for proper wound healing in vivo.
Rhea L et al.
Developmental Dynamics : an Official Publication of the American Association of Anatomists, 2020
A Novel Van der Woude Syndrome-Causing IRF6 Variant Is Subject to Incomplete Non-sense-Mediated mRNA Decay Affecting the Phenotype of Keratinocytes.
Degen M et al.
Frontiers in Cell and Developmental Biology, 2020
MicroRNA-655-3p and microRNA-497-5p inhibit cell proliferation in cultured human lip cells through the regulation of genes related to human cleft lip.
Gajera M et al.
Bmc Medical Genomics, 2019
[Clinical and genetic features of Chinese kindreds with Van der Woude syndrome caused by interferon regulatory factor 6 mutation].
Du XY et al.
Hua Xi Kou Qiang Yi Xue Za Zhi = Huaxi Kouqiang Yixue Zazhi = West China Journal of Stomatology, 2018
Association between genotype and phenotype of virulence gene in Van der Woude syndrome families.
Li S et al.
Molecular Medicine Reports, 2018
Interferon Regulatory Factor 6 Controls Proliferation of Keratinocytes From Children With Van der Woude Syndrome.
Hixon K et al.
The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-craniofacial Association, 2017
Tooth agenesis and orofacial clefting: genetic brothers in arms?
Phan M et al.
Human Genetics, 2016
Disease-associated mutations in IRF6 and RIPK4 dysregulate their signalling functions.
Kwa MQ et al.
Cellular Signalling, 2015
Expanding the genetic and phenotypic spectrum of popliteal pterygium disorders.
Leslie EJ et al.
American Journal of Medical Genetics. Part A, 2015
Novel lip pit phenotypes and mutations of IRF6 in Van der Woude syndrome patients from Pakistan.
Malik S et al.
Clinical Genetics, 2014
Comparative analysis of IRF6 variants in families with Van der Woude syndrome and popliteal pterygium syndrome using public whole-exome databases.
Leslie EJ et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2013
Prevalence and nonrandom distribution of exonic mutations in interferon regulatory factor 6 in 307 families with Van der Woude syndrome and 37 families with popliteal pterygium syndrome.
de Lima RL et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2009
Identification of IRF6 gene variants in three families with Van der Woude syndrome.
Tan EC et al.
International Journal of Molecular Medicine, 2008
A novel IRF6 nonsense mutation (Y67X) in a German family with Van der Woude syndrome.
Brosch S et al.
International Journal of Molecular Medicine, 2007
Novel IRF6 mutations in Chinese patients with Van der Woude syndrome.
Du X et al.
Journal of Dental Research, 2006
[Identification of three novel mutations of IRF6 in Chinese families with Van der Woude syndrome].
Du XY et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics, 2006
Novel and de novo mutations of the IRF6 gene detected in patients with Van der Woude or popliteal pterygium syndrome.
Peyrard-Janvid M et al.
European Journal of Human Genetics : Ejhg, 2005
Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes.
Kondo S et al.
Nature Genetics, 2002
Novel IRF6 mutations in Honduran Van der Woude syndrome patients.
Birkeland AC et al.
Molecular Medicine Reports, 0