Associated Papers
Monogenic disorders of the IRF transcription factors.
Stojcic MP et al.
The Journal of Experimental Medicine, 2026
Ancestry-dependent patterns of somatic mosaicism and clonal hematopoiesis mutations in over 125,000 individuals reveal distinct cancer associations.
Colin-Leitzinger C et al.
Human Genomics, 2025
Integrating genomic and transcriptome features for characterization and prognostic prediction of angioimmunoblastic T-cell lymphoma.
Wei C et al.
Annals of Hematology, 2025
Distinct characteristics of lymphoid and myeloid clonal hematopoiesis in World Trade Center first responders.
Esai Selvan M et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
A novel dominant-negative variant of IRF8 in a mother and son: Clinical, phenotypic and biological characteristics.
Ham H et al.
The Journal of Allergy and Clinical Immunology, 2025
Clonal hematopoiesis is associated with distinct rheumatoid arthritis phenotypes.
Hiitola E et al.
Science Advances, 2025
Peripheral blood somatic mosaicism and clonal hematopoiesis across ancestry backgrounds.
Colin-Leitzinger C et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
Case Report: A patient with a novel heterozygous IRF8 variant with repeated infection and immune-mediated organ disease, but without disseminated mycobacterial disease despite BCG immunization.
Chiang SCC et al.
Frontiers in Immunology, 2025
Characterizing the Mutational Landscape of Diffuse Large B-Cell Lymphoma in a Prospective Cohort of Mexican Patients.
Candelaria M et al.
International Journal of Molecular Sciences, 2024
IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHCII complexes.
Qiu Z et al.
Science Advances, 2024
Murine IRF8 Mutation Offers New Insight into Osteoclast and Root Resorption.
Das A et al.
Journal of Dental Research, 2024
IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHC CII complexes.
Qiu Z et al.
Biorxiv : the Preprint Server for Biology, 2023
Transcription-independent regulation of STING activation and innate immune responses by IRF8 in monocytes.
Luo WW et al.
Nature Communications, 2022
Circulating tumor DNA for comprehensive noninvasive monitoring of lymphoma treated with ibrutinib plus nivolumab.
Bruscaggin A et al.
Blood Advances, 2021
MAPK and JAK-STAT pathways dysregulation in plasmablastic lymphoma.
Ramis-Zaldivar JE et al.
Haematologica, 2021
An updated review on Mendelian susceptibility to mycobacterial diseases- a silver jubilee celebration of its first genetic diagnosis.
Das J et al.
Expert Review of Clinical Immunology, 2021
Treating primary immunodeficiencies with defects in NK cells: from stem cell therapy to gene editing.
Eguizabal C et al.
Stem Cell Research & Therapy, 2020
Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans.
Cytlak U et al.
Immunity, 2020
Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases.
Salem S et al.
Human Genetics, 2020
Inactivating Mutation in IRF8 Promotes Osteoclast Transcriptional Programs and Increases Susceptibility to Tooth Root Resorption.
Thumbigere-Math V et al.
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 2019
Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.
Bigley V et al.
The Journal of Allergy and Clinical Immunology, 2018
Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets.
Karube K et al.
Leukemia, 2018
Biallelic mutations in IRF8 impair human NK cell maturation and function.
Mace EM et al.
The Journal of Clinical Investigation, 2017
Dendritic cell analysis in primary immunodeficiency.
Bigley V et al.
Current Opinion in Allergy and Clinical Immunology, 2016
Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.
Lilljebjörn H et al.
Nature Communications, 2016
Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunity.
Bustamante J et al.
Seminars in Immunology, 2014
Host genetic factors in susceptibility to mycobacterial disease.
Duncan CJ et al.
Clinical Medicine (london, England), 2014
Innate defects of the IL-12/IFN-γ axis in susceptibility to infections by mycobacteria and salmonella.
Ramirez-Alejo N et al.
Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research, 2014
Nontuberculous mycobacterial infections in children with inborn errors of the immune system.
Haverkamp MH et al.
The Journal of Infection, 2014
High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias.
Waterfall JJ et al.
Nature Genetics, 2014
Genetic determinants of susceptibility to Mycobacterial infections: IRF8, a new kid on the block.
Salem S et al.
Advances in Experimental Medicine and Biology, 2013
Bacillus Calmette-Guérin (BCG) complications associated with primary immunodeficiency diseases.
Norouzi S et al.
The Journal of Infection, 2012
Immune defects in active mycobacterial diseases in patients with primary immunodeficiency diseases (PIDs).
Lee WI et al.
Journal of the Formosan Medical Association = Taiwan Yi Zhi, 2011
Human dendritic cell deficiency: the missing ID?
Collin M et al.
Nature Reviews. Immunology, 2011
IRF8 mutations and human dendritic-cell immunodeficiency.
Hambleton S et al.
The New England Journal of Medicine, 2011