Varaico: Literature-Extracted Genetic Variants

Gene:IRF8
Variant:p.K66R
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IRF8

NM_002163.4:p.K66R

Associated Papers

Pediatric-type follicular lymphoma and pediatric nodal marginal zone lymphoma: additional evidence to support they are a single disease with variation in the histologic spectrum.

Li HG et al.

Virchows Archiv : an International Journal of Pathology, 2024

IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHCII complexes.

Qiu Z et al.

Science Advances, 2024

38996030 (PubMed )
Supplement: sciadv.adk2091_sm.pdf

Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes.

Noerenberg D et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2024

38055913 (PubMed )
Supplement: DS3_JCO.23.01053.xlsx › Table_S2.7

IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHC CII complexes.

Qiu Z et al.

Biorxiv : the Preprint Server for Biology, 2023

The clinical and molecular taxonomy of t(14;18)-negative follicular lymphomas.

Salaverria I et al.

Blood Advances, 2023

Personalized monitoring of circulating tumor DNA with a specific signature of trackable mutations after chimeric antigen receptor T-cell therapy in follicular lymphoma patients.

Jiménez-Ubieto A et al.

Frontiers in Immunology, 2023

37342332 (PubMed )
Supplement: Table_2.xlsx › Sheet1

Case report: Clinicopathological and molecular characteristics of pediatric-type follicular lymphoma.

Ren B et al.

Frontiers in Pediatrics, 2023

Pediatric-Type Indolent B-Cell Lymphomas With Overlapping Clinical, Pathologic, and Genetic Features.

Lim S et al.

The American Journal of Surgical Pathology, 2022

A unifying hypothesis for PNMZL and PTFL: morphological variants with a common molecular profile.

Salmeron-Villalobos J et al.

Blood Advances, 2022

Point Mutation Specific Antibodies in B-Cell and T-Cell Lymphomas and Leukemias: Targeting IDH2, KRAS, BRAF and Other Biomarkers RHOA, IRF8, MYD88, ID3, NRAS, SF3B1 and EZH2.

Singh K et al.

Diagnostics (basel, Switzerland), 2021

Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole-exome sequencing.

Zamò A et al.

Leukemia, 2018

28824170 (PubMed )
Supplement: 41375_2018_BFleu2017270_MOESM101_ESM.xlsx › S_Table_3b

Mutations of MAP2K1 are frequent in pediatric-type follicular lymphoma and result in ERK pathway activation.

Schmidt J et al.

Blood, 2017

A study of the mutational landscape of pediatric-type follicular lymphoma and pediatric nodal marginal zone lymphoma.

Ozawa MG et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."